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Merck
CN
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文件

21953

Sigma-Aldrich

5(6)-羧甲基四甲基罗丹明

BioReagent, suitable for fluorescence, ≥85% (sum of isomers, HPCE)

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About This Item

经验公式（希尔记法）:
C25H22N2O5
CAS号:
98181-63-6
分子量:
430.45
MDL编号:
MFCD16661194
UNSPSC代码:
12352116
PubChem化学物质编号:
329752227
NACRES:
NA.32

产品线

BioReagent

质量水平

100

检测方案

≥85% (sum of isomers, HPCE)

形式

solid

mp

≥300 °C (lit.)

溶解性

DMF: soluble
DMSO: soluble

荧光

λex 543 nm; λem 572 nm in methanol

适用性

suitable for fluorescence

SMILES字符串

CN(C)c1ccc2c(Oc3cc(ccc3C24OC(=O)c5cc(ccc45)C(O)=O)N(C)C)c1.CN(C)c6ccc7c(Oc8cc(ccc8C79OC(=O)c%10ccc(cc9%10)C(O)=O)N(C)C)c6

InChI

1S/2C25H22N2O5/c1-26(2)15-6-9-19-21(12-15)31-22-13-16(27(3)4)7-10-20(22)25(19)18-8-5-14(23(28)29)11-17(18)24(30)32-25;1-26(2)15-6-9-18-21(12-15)31-22-13-16(27(3)4)7-10-19(22)25(18)20-11-14(23(28)29)5-8-17(20)24(30)32-25/h2*5-13H,1-4H3,(H,28,29)

InChI key

LBUFYZITRTUEFI-UHFFFAOYSA-N

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相关类别

应用

5（6）-羧基四甲基罗丹明（TAMRA，TMR）在研究细胞穿透肽（CPPs）等分子的分布时可用作荧光探针，在二维荧光强度分布分析（2D-FIDA）、荧光共振能量转移（LRET）和荧光共振能量转移（FRET）等应用中可作为荧光伴侣。
与蛋白质、核酸和其他生物分子上的伯胺和仲胺基反应。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Jinliang Liu et al.
Biosensors & bioelectronics, 43, 252-256 (2013-01-16)
In this short communication we report an efficient and versatile method for the detection of methicillin-resistant staphylococcus aureus (MRSA) DNA sequence with high sensitivity and specificity. This method is based on upconversion nanoparticles (UCNs) and luminescence resonance energy transfer (LRET)
Dongyun Liu et al.
The AAPS journal, 15(1), 288-298 (2012-12-01)
Peptide and protein drugs have become the new generation of therapeutics, yet most of them are only available as injections, and reports on oral local intestinal delivery of peptides and proteins are quite limited. The aim of this work was
P Kask et al.
Biophysical journal, 78(4), 1703-1713 (2000-03-29)
A method of sample analysis is presented which is based on fitting a joint distribution of photon count numbers. In experiments, fluorescence from a microscopic volume containing a fluctuating number of molecules is monitored by two detectors, using a confocal
Daniel Renčiuk et al.
Methods (San Diego, Calif.), 57(1), 122-128 (2012-04-03)
Some of the most serious diseases are characterized by the presence of a specific secondary structure within DNA or RNA, often in the promoter or the coding region of the responsible gene, that enhances or disrupts expression of the protein.
Yoshiaki Yano et al.
Biochemistry, 41(9), 3073-3080 (2002-02-28)
Investigation of interactions between hydrophobic model peptides and lipid bilayers is perhaps the only way to elucidate the principles of the folding and stability of membrane proteins (White, S. H., and Wimley, W. C. (1998) Biochim. Biophys. Acta 1367, 339-352).
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