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Merck
CN
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21878

Sigma-Aldrich

5 (6)-羧基荧光素 N -羟基琥珀酰亚胺酯

BioReagent, suitable for fluorescence, mixture of isomers, ≥80% (HPLC)

别名:

5 (6)-溶剂, FLUOS

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About This Item

经验公式（希尔记法）:
C25H15NO9
CAS号:
117548-22-8
分子量:
473.39
MDL编号:
MFCD04119713
UNSPSC代码:
12352108
PubChem化学物质编号:
57647947
NACRES:
NA.32

质量水平

200

产品线

BioReagent

检测方案

≥80% (HPLC)

形式

powder

溶解性

DMF: soluble
DMSO: soluble

荧光

λex 492 nm; λem 517 nm in DMF

适用性

suitable for fluorescence

储存温度

−20°C

SMILES字符串

OC(=O)c1ccc(cc1C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24)C(=O)ON5C(=O)CCC5=O.OC(=O)c6cccc(C(=O)ON7C(=O)CCC7=O)c6C8=C9C=CC(=O)C=C9Oc%10cc(O)ccc8%10

InChI

1S/2C25H15NO9/c27-13-2-5-16-19(10-13)34-20-11-14(28)3-6-17(20)23(16)18-9-12(1-4-15(18)24(31)32)25(33)35-26-21(29)7-8-22(26)30;27-12-4-6-14-18(10-12)34-19-11-13(28)5-7-15(19)22(14)23-16(24(31)32)2-1-3-17(23)25(33)35-26-20(29)8-9-21(26)30/h1-6,9-11,27H,7-8H2,(H,31,32);1-7,10-11,27H,8-9H2,(H,31,32)

InChI key

YVTPVJDECOUTJW-UHFFFAOYSA-N

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应用

5 (6)-羧基荧光素 N -羟基琥珀酰亚胺酯 (5 (6)-FAM SE, FLUOS) 可用于制备蛋白质如微管蛋白的荧光衍生物，并用于制备苯妥英示踪剂，以通过荧光偏振免疫分析 (FPIA) 和激光诱导荧光检测测定血清和血浆中该药物和其他药物。
已用于制备微管蛋白的荧光衍生物，并用于制备苯妥英示踪剂，以通过荧光偏振免疫分析法 (FPIA) 测定血清和血浆中该药物
蛋白质和其他生物分子上伯胺和仲胺基团的荧光标记。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

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International journal of molecular sciences, 21(19) (2020-10-01)
In this study, we aimed to develop a multifunctional drug/gene delivery system for the treatment of glioblastoma multiforme by combining the ligand-mediated active targeting and the pH-triggered drug release features of graphene oxide (GO). Toward this end, we load irinotecan
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