10940
N-辛酰- DL -高丝氨酸内酯
≥97.0% (HPLC)
别名:
N-辛酰- DL -高丝氨酸内酯
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关于此项目
经验公式（希尔记法）:
C12H21NO3
化学文摘社编号:
分子量:
227.30
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
1642628
MDL number:
产品名称
N-辛酰- DL -高丝氨酸内酯, ≥97.0% (HPLC)
SMILES string
CCCCCCCC(=O)NC1CCOC1=O
InChI
1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)
InChI key
JKEJEOJPJVRHMQ-UHFFFAOYSA-N
assay
≥97.0% (HPLC)
form
powder with small lumps
color
white to faintly beige
application(s)
detection
storage temp.
2-8°C
Quality Level
Application
应用试验：在通常不能产生高丝氨酸内酯的紫色色杆菌突变体中诱导紫色素表达。
Biochem/physiol Actions
N-辛酰-高丝氨酸内酯 (N-C8-HSL) 是一类高丝氨酸内酯，包括；N-庚酰-DL-高丝氨酸内酯 (C7HSL)、N-癸酰-DL-高丝氨酸内酯 (N-C10-HSL)、N-（3-氧癸酰）高丝氨酸-L-内酯 (3-oxo-C10 HSL)、N-（3-氧十二酰）高丝氨酸-L-内酯 (3-oxo-C12-HSL)、N-（3-氧十四酰）-L-高丝氨酸内酯 (3-oxo-C14-HSL)、N-（3-羟基癸酰）-L-高丝氨酸内酯和 N-（3-羟基辛酰基）-L-高丝氨酸内酯参与细菌群体感应过程。这些 N-酰基-高丝氨酸内酯被用于研究细菌群体感应的过程和机制。
N-辛酰基-DL-高丝氨酸内酯是N-酰基-高丝氨酸内酯家族的成员。N-酰基高丝氨酸内酯（AHL）调节革兰氏阴性菌中的基因表达，例如埃希氏杆菌和沙门氏菌涉及细菌间的群体感应、细胞间通讯。一些AHL是人类免疫细胞（如嗜中性粒细胞）的强效化学诱导剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Hebert F Culler et al.
Genes, 9(5) (2018-05-16)
Atypical enteropathogenic Escherichia coli are capable to form biofilm on biotic and abiotic surfaces, regardless of the adherence pattern displayed. Several E. coli mechanisms are regulated by Quorum sensing (QS), including virulence factors and biofilm formation. Quorum sensing is a
Hongsup Kim et al.
Journal of bacteriology, 194(5), 982-992 (2011-12-20)
Burkholderia glumae possesses a quorum-sensing (QS) system mediated by N-octanoyl-homoserine lactone (C(8)-HSL) and its cognate receptor TofR. TofR/C(8)-HSL regulates the expression of a transcriptional regulator, qsmR. We identified one of the universal stress proteins (Usps), Usp2, from a genome-wide analysis
Xinqi Huang et al.
Current microbiology, 74(1), 68-76 (2016-11-04)
Marine algae provide a unique niche termed the phycosphere for microorganism inhabitation. The phycosphere environment is an important niche for mutualistic and competitive interactions between algae and bacteria. Quorum sensing (QS) serves as a gene regulatory system in the microbial
Francisco Pérez-Montaño et al.
Research in microbiology, 162(7), 715-723 (2011-05-24)
Legume-nodulating rhizobia use N-acyl homoserine lactones (AHLs) to regulate several physiological traits related to the symbiotic plant-microbe interaction. In this work, we show that Sinorhizobium fredii SMH12, Rhizobium etli ISP42 and Rhizobium sullae IS123, three rhizobial strains with different nodulation
Frank Wilco Bartels et al.
Biophysical journal, 92(12), 4391-4400 (2007-03-27)
Intercellular communication by means of small signal molecules coordinates gene expression among bacteria. This population density-dependent regulation is known as quorum sensing. The symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti Rm1021 possesses the Sin quorum sensing system based on N-acyl homoserine lactones
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