09945
正丁酰基-DL-高丝氨酸内酯
≥96.0% (HPLC)
别名:
N-(tetrahydro-2-oxo-3-furanyl)-Butanamide
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关于此项目
经验公式（希尔记法）:
C8H13NO3
化学文摘社编号:
分子量:
171.19
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
6375
MDL number:
产品名称
正丁酰基-DL-高丝氨酸内酯, ≥96.0% (HPLC)
SMILES string
CCCC(=O)NC1CCOC1=O
CCCC(=O)NC1CCOC1=O
InChI
1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)
InChI key
VFFNZZXXTGXBOG-UHFFFAOYSA-N
assay
≥96.0% (HPLC)
form
powder or crystals
color
white to faint beige
Quality Level
Application
应用试验：在通常不能产生高丝氨酸内酯的紫色色杆菌突变体中诱导紫色素表达。
Biochem/physiol Actions
N-丁酰基-DL-高丝氨酸内酯是N-酰基-高丝氨酸内酯家族的成员。N-酰基高丝氨酸内酯（AHL）调节革兰氏阴性菌中的基因表达，例如埃希氏杆菌和沙门氏菌涉及细菌间的群体感应、细胞间通讯。一些AHL是人类免疫细胞（如嗜中性粒细胞）的强效化学诱导剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Longyi Lv et al.
Journal of hazardous materials, 354, 72-80 (2018-05-08)
Quorum sensing (QS) signalling has been extensively studied in single species populations, activated sludge, biofilm and aerobic granular sludge. However, ecological roles of QS in anaerobic granular sludge, particularly in the content of the relationship between QS signalling and microbial
Thommie Karlsson et al.
Journal of leukocyte biology, 91(1), 15-26 (2011-08-03)
In gram-negative bacteria, cell-cell communication based on HSL QS molecules is known to coordinate the production of virulence factors and biofilms. These bacterial signals can also modulate human immune cell behavior. Using a Transwell migration assay, we found that human
Tomohiro Morohoshi et al.
FEMS microbiology letters, 279(1), 124-130 (2008-01-08)
In tests, Chromobacterium violaceum ATCC 12472 produced several N-acyl-L-homoserine lactones (AHLs). Of these, N-(3-hydroxydecanoyl)-L-homoserine lactone was dominant, and controlled violacein production by quorum sensing. Strain VIR07, an AHL-deficient mutant, did not produce violacein. Violacein production in VIR07 was induced by
L Eberl
Systematic and applied microbiology, 22(4), 493-506 (2000-05-04)
The view of bacteria as unicellular organisms has strong roots in the tradition of culturing bacteria in liquid media. However, in nature microbial activity is mainly associated with surfaces where bacteria form highly structured and cooperative consortia which are commonly
Joanne Hothersall et al.
Applied microbiology and biotechnology, 90(3), 1017-1026 (2011-02-15)
Transcription of the 74 kb Pseudomonas fluorescens mupirocin [pseudomonic acid (PA)] biosynthesis cluster depends on quorum sensing-dependent regulation via the LuxI/LuxR homologues MupI/MupR. To facilitate analysis of novel PAs from pathway mutants, we investigated factors that affect mup gene expression.
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