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Merck
CN

02286

Kollidon ® 25

别名:

聚乙烯吡咯烷酮, PVP, 聚维酮

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线性分子式:
(C6H9NO)n
化学文摘社编号:
NACRES:
NA.25
UNSPSC Code:
12162002
MDL number:
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SMILES string

C=CN1CCCC1=O
C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

impurities

≤1 ppm hydrazine
≤10 ppm heavy metals (verified on random samples only)
≤10 ppm lead (verified on random samples only)
≤10 ppm vinylpyrrolidinone
≤3.0% 2-pyrrolidone
≤400 ppm peroxides (as H2O2)
≤5.0% water
≤500 ppm aldehydes (as acetaldehyde)
≤5000 ppm formic acid
12.0-12.8% nitrogen (anhydrous basis)

ign. residue

≤0.1% (verified on random samples only)

pH

3.0-5.0

suitability

complies for Infrared spectrum

application(s)

sample preservation

Quality Level

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Application

Kollidon 产品由不同分子量和粒度的可溶性和不溶性聚乙烯吡咯烷酮 (PVP) 组成。用作干粘合剂、成膜剂、悬浮液中的稳定剂、颜料分散剂、酶稳定剂和生物利用度改进剂。
Kollidon SR 是聚醋酸乙烯酯和聚维酮 (K 30) 的混合物,比例为 8:2,用作基质形成剂。该研究级产品预期用于研发。

Other Notes

聚乙烯吡咯烷酮是 Denhardt′s 溶液的一种成分,在标准 50X 储备溶液中的浓度为 1%(w/v)。

Legal Information

Kollidon is a registered trademark of BASF SE

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yan-Yan Yin et al.
Inorganic chemistry, 51(8), 4784-4790 (2012-03-31)
Chiral Ni(II) coordination compounds with structures of [NiL(H(2)O)(3)] (1) and {[NiL(H(2)O)]·0.5H(2)O}(n) (2) (H(2)L = thiazolidine 2,4-dicaboxlic acid) have been successfully synthesized by the reaction of Ni(CH(3)COO)(2)·4H(2)O and H(2)L in aqueous solution at 25 and 80 °C, respectively. From the same
Camila Braga Dornelas et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 14(1), 17-35 (2011-04-20)
This work describes the preparation of new nanocomposites based on lamellar silicates (AAM-alkyl ammonium montmorillonite) obtained by the intercalation of PVP K30 and glyceril monostearate. By XRD, TGA and DSC analysis the AAM was characterized and its compactation characteristics, functionality
Jianxin Zhang et al.
International journal of pharmaceutics, 414(1-2), 210-217 (2011-06-02)
Nanothermal analysis (NTA) supported by atomic force microscopy imaging has been used to study the changes that occur at the surfaces of solid dispersions of the drug felodipine and the water soluble polymer, polyvinylpyrrolidone (PVP) on exposure to standard pharmaceutical
Ajit S Narang et al.
Journal of pharmaceutical sciences, 101(1), 127-139 (2011-11-24)
Reactive peroxides in povidone often lead to degradation of oxidation-labile drugs. To reduce peroxide concentration in povidone, the roles of storage conditions, antioxidants, and silicates were investigated. Povidone alone and its physical mixtures with ascorbic acid, propyl gallate, sodium sulfite
Doris Bach et al.
Journal of photochemistry and photobiology. B, Biology, 120, 74-81 (2013-03-08)
Photodynamic therapy (PDT) is a local tumour treatment accepted for a number of indications. PDT operates via the cellular stress response through the production of reactive oxygen species and subsequent cellular damage, resulting in cell death. Although PDT-induced signalling and

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