推荐产品
等级
pharmaceutical primary standard
API类
acemetacin
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-8°C
SMILES字符串
COc1ccc2n(c(C)c(CC(=O)OCC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3
InChI
1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25)
InChI key
FSQKKOOTNAMONP-UHFFFAOYSA-N
基因信息
human ... PTGS1(5742) , PTGS2(5743)
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Acemetacin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
生化/生理作用
该非甾体抗炎药 (NSAID) 专门增强蒽环类药（阿霉素、柔红霉素和 epirubium）的细胞毒性。避免 MRP 介导的多药耐药性。
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
警示用语：
Danger
危险分类
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
WGK
WGK 3
[Clinical profile of acemetacin].
H Rechziegler et al.
Medizinische Klinik (Munich, Germany : 1983), 85(5), 340-346 (1990-05-15)
R Andrew Moore et al.
The Cochrane database of systematic reviews, (3)(3), CD007589-CD007589 (2009-07-10)
Acemetacin is a non-steroidal anti-inflammatory drug (NSAID) licensed for use in rheumatic disease and other musculoskeletal disorders in the UK, and widely available in other countries worldwide. This review sought to evaluate the efficacy and safety of oral acemetacin in
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