产品名称
TWEEN® 40, viscous liquid
SMILES string
O1C(C(C(C1)OCCO)OCCO)C(OCCO)COCCOC(=O)CCCCCCCCCCC
InChI
1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
InChI key
HMFKFHLTUCJZJO-UHFFFAOYSA-N
description
non-ionic
assay
~90.0% (GC)
form
viscous liquid
mol wt
estimated mol wt 1277
composition
Palmitic acid, ~90.0% (balance primarily stearic acid)
greener alternative product characteristics
Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
CMC
0.027 (20-25°C)
solubility
water: 100 mg/mL, clear to slightly hazy, faintly yellow
HLB
15.6
greener alternative category
, Aligned
Quality Level
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Legal Information
ECO TWEEN is a registered trademark of Croda Inc.
TWEEN is a registered trademark of Croda International PLC
Application
Non-ionic detergent used for cell lysis, nuclei isolation and cell fractionation.
Polyoxyethylenesorbitan monopalmitate, or Tween® 40, has been used in a study to assess the determination of iodide in urine based on a chemiluminescence system. It has also been used in a study to investigate the delivery of astaxanthin and canthaxanthin to HepG2 cells.
Features and Benefits
- 100 % Renewable
- 100 % Bio-based
- Certified to the USDA BioPreferred Program
- Lower carbon footprint than petrochemical-based versions
- High-purity chemical suitable for a wide variety of research applications
General description
ECO Tween® 40, also known as Polyoxyethylenesorbitan monopalmitate, is a bio-based, nonionic detergent manufactured from natural fatty acid (palmitic acid). This surfactant, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting. Its versatility makes it well-suited for a variety of applications in biochemical and biological research, with common uses including cell lysis, nuclei isolation and cell fractionation.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation".
Other Notes
For additional information on our range of Biochemicals, please complete this form.
存储类别
10 - Combustible liquids
wgk
WGK 1
Determination of iodide in urine based on chemiluminescence system of cerium (IV)-tween 40-iodide
Li and Xie
Journal of Luminescence, 132, 5-5 (2012)
Christine Boesch-Saadatmandi et al.
Cytotechnology, 63(1), 89-97 (2010-12-15)
The present investigation aimed to compare fetal calf serum (FCS) and Tween 40 with the commonly employed tetrahydrofuran (THF) with respect to cytotoxicity, stability of the solubilized carotenoids, and uptake and accumulation of the xanthophylls astaxanthin (AX) and canthaxanthin (CX)
J G Culvenor et al.
Journal of cellular biochemistry, 20(2), 127-138 (1982-01-01)
Plasma membrane was isolated from the mouse T lymphoma cell line WEHI-22 using four different methods of cell disruption followed by centrifugal fractionation. Disruption by nitrogen cavitation or by shearing with a cell pump produced plasma membrane vesicles of similar
Branka Rozman et al.
Drug delivery, 14(4), 235-245 (2007-05-15)
An interesting strategy for protecting skin from excessive exposure to free radicals is to support the skin endogenous antioxidant system. As the balance between different skin antioxidants is very important, a combined therapy using at least two antioxidants is desirable.
Sinead M O'Sullivan et al.
The British journal of nutrition, 91(5), 757-764 (2004-05-13)
Epidemiological evidence suggests that dietary intake of carotenoids and tocopherols may influence the risk of certain chronic diseases, such as cancer and CVD. In vitro studies investigating the synergistic effects of mixtures of carotenoids and tocopherols have been hindered due
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