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等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to Ph. Eur. Y0001028
traceable to USP 1249789
API类
omeprazole
CofA
current certificate can be downloaded
包装
ampule of 1 g
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-30°C
SMILES字符串
[Mg+2].[S](=O)(Cc6ncc(c(c6C)OC)C)c4[n-]c5c(n4)cc(cc5)OC.[S](=O)(Cc3ncc(c(c3C)OC)C)c1[n-]c2c(n1)cc(cc2)OC.O.O.O
InChI
1S/2C17H18N3O3S.Mg.3H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;;;/h2*5-8H,9H2,1-4H3;;3*1H2/q2*-1;+2;;;
InChI key
VEVZQDGATGBLIC-UHFFFAOYSA-N
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相关类别
一般描述
Esomeprazole Magnesium is theS-isomer of omeprazole and is widely used for the treatment of acid related diseases. It is the first single optical isomer proton pump inhibitor and is found to be better over omeprazole in terms of pharmacokinetic characteristics and acid suppression.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
应用
Esomeprazole Magnesium may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using UV-Vis spectroscopy technique and spectrophotometric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAC1677 in the slot below. This is an example certificate only and may not be the lot that you receive.
相关产品
产品编号
说明
价格
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Spectrophotometric Determination of Esomeprazole Magnesium in Commercial Tablets Using 5?Sulfosalicylic Acid and N?Bromosuccinimide
Rahman N, et al.
J. Chin. Chem. Soc., 55(3), 557-566 (2008)
Development and validation of analytical methods for Simultaneous estimation of domperidone and esomeprazole Magnesium in bulk and in pharmaceutical formulations Using UV-Visible spectroscopy
BPD, et al.
Development, 6(5), 1501-1508 (2014)
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