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经验公式（希尔记法）:
C17H19N3O3S
化学文摘社编号:
分子量:
345.42
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
奥美拉唑, United States Pharmacopeia (USP) Reference Standard
InChI key
SUBDBMMJDZJVOS-UHFFFAOYSA-N
SMILES string
COc1ccc2[nH]c(nc2c1)S(=O)Cc3ncc(C)c(OC)c3C
InChI
1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
grade
pharmaceutical primary standard
API family
omeprazole
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Gene Information
human ... ATP4A(495), ATP4B(496)
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Omeprazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Esomeprazole Magnesium
- Esomeprazole Magnesium Delayed-Release Capsules
- Esomeprazole Strontium
- Omeprazole
- Omeprazole Delayed-Release Capsules
- Omeprazole Magnesium
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.Omeprazole is a benzimidazole derivative, which exhibits antisecretory and antiulcer properties. It is a drug with selective and irreversible proton pump inhibition activity, widely used in the treatment of duodenal, gastric ulcers, reflux oesophagitis, and against other acid-related diseases.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Development and validation of a RP-HPLC method for the quantification of omeprazole in pharmaceutical dosage form
Kayesh R, et al.
Journal of Scientific Research, 5(2), 335-342 (2013)
The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: implications for coadministration with clopidogrel
Ogilvie BW, et al.
Drug Metabolism and Disposition, 39(11), 2020-2033 (2011)
Extractive spectrophotometric determination of omeprazole in pharmaceutical preparations
Bhandage A, et al.
Tropical Journal of Pharmaceutical Research, 8(5) (2009)
Determination of omeprazole in bulk and injectable preparations by liquid chromatography
Schubert A, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 86(3), 501-504 (2003)
Analytical method development and validation for the determination of omeprazole and aspirin using reverse phase hplc method in bulk and dosage form
Vani, R and Sunitha, M
Journal of Pharmacological Sciences, 2(4), 25-29 (2017)
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