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PHR1379

硫酸阿托品

Name: 硫酸阿托品
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

阿托品硫酸盐一水合物, (8-甲基-8-氮杂双环[3.2.1]辛-3-基) edno-(+/-)-α-(羟甲基)苯乙酸酯, 龙葵碱

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About This Item

线性分子式:

(C₁₇H₂₃NO₃)₂ · H₂SO₄ · H₂O

CAS号:

5908-99-6

分子量:

694.83

Beilstein:

6109275

EC 号:

200-235-0

MDL编号:

MFCD00074815

UNSPSC代码:

41116107

PubChem化学物质编号:

329823356

NACRES:

NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 23
traceable to Ph. Eur. A1400000
traceable to USP 1045009

API类

atropine

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

189-192 °C (A) (lit.)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6

InChI

1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;

InChI key

JPKKQJKQTPNWTR-CHYDPLAESA-N

基因信息

human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atropine Sulfate is an alkaloid extracted from belladonna herb. It is a cholinergic drug, administered as an anti-arrhythmic medicine.

应用

Atropine Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrophoresis and chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

位于中枢和外周毒蕈碱型乙酰胆碱受体处的竞争性非选择性拮抗剂。

附注

To see an example of a Certificate of Analysis for this material enter LRAC4087 in the slot below. This is an example certificate only and may not be the lot that you receive.

警示用语：

Danger

危险声明

H300 + H330

预防措施声明

P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233

危险分类

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Determination of atropine in pharmaceutical preparations by liquid chromatography with fluorescence detection.

Takahashi M, et al.

Journal of Chromatography A, 775(1-2), 137-141 (1997)

Determination of atropine sulfate using a novel sensitive DNA-biosensor based on its interaction on a modified pencil graphite electrode.

Ensafi AA, et al.

Talanta, 131, 149-155 (2015)

LC determination of atropine sulfate and scopolamine hydrobromide in pharmaceuticals.

Ceyhan T, et al.

Journal of Pharmaceutical and Biomedical Analysis, 25(3-4), 399-406 (2001)

Development and validation of a capillary zone electrophoresis method for the determination of atropine, homatropine and scopolamine in ophthalmic solutions.

Cherkaoui S, et al.

Journal of Chromatography. B, Biomedical Sciences and Applications, 696(2), 283-290 (1997)

Involvement of neurotransmitters in the action of the nociceptin/orphanin FQ peptide-receptor system on passive avoidance learning in rats.

Miklós Palotai et al.

Neurochemical research, 39(8), 1477-1483 (2014-06-05)

The nociceptin/orphanin FQ peptide (NOP) receptor and its endogenous ligand plays role in several physiologic functions of the central nervous system, including pain, locomotion, anxiety and depression, reward and drug addiction, learning and memory. Previous studies demonstrated that the NOP-receptor

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文件

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硫酸阿托品

Pharmaceutical Secondary Standard; Certified Reference Material

About This Item

属性

等级

质量水平

Agency

API类

CofA

技术

mp

应用

格式

储存温度

SMILES字符串

InChI

InChI key

基因信息

相关类别

说明

一般描述

应用

生化/生理作用

附注

相关产品

相关产品

安全信息

象形图

警示用语：

危险声明

预防措施声明

危险分类

WGK

闪点(°F)

闪点(°C)

法规信息

文件

分析证书(COA)

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