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文件

PHR1258

磷酸氯喹

Name: 磷酸氯喹
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

氯喹二磷酸盐, N⁴-(7-氯-4-喹啉基)-N¹,N¹-二甲基-1,4-戊二胺二磷酸盐

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About This Item

经验公式（希尔记法）:

C₁₈H₂₆ClN₃ · 2H₃PO₄

CAS号:

50-63-5

分子量:

515.86

Beilstein:

4223142

EC 号:

200-055-2

MDL编号:

MFCD00069852

UNSPSC代码:

41116107

PubChem化学物质编号:

329823259

NACRES:

NA.24

生物来源

synthetic

质量水平

300

等级

certified reference material
pharmaceutical secondary standard

Agency

BP
EP
USP
traceable to USP 1118000

蒸汽压

<0.0000001 kPa ( 25 °C)

API类

chloroquine

CofA

current certificate can be downloaded

包装

pkg of 1 g

储存条件

protect from light

技术

HPLC: suitable
gas chromatography (GC): suitable

颜色

white to yellow

pH值（酸碱度）

3.5-4.5 (10% in aqueous solution, pH <6.0)

mp

200 °C (dec.) (lit.)

溶解性

water: 50 g/L
benzene: practically insoluble
chloroform: practically insoluble
ethanol: practically insoluble
ether: practically insoluble

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

OP(O)(O)=O.OP(O)(O)=O.CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI

1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)

InChI key

QKICWELGRMTQCR-UHFFFAOYSA-N

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一般描述

用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

磷酸氯喹是氯喹的磷酸盐，属于氨基喹啉类药物，用作抗疟药和抗阿米巴药。

应用

磷酸氯喹可用作药物参考标准品，通过薄层色谱(TLC)和液相色谱(LC)技术测定药物制剂中的分析物。

这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

这些二级标准提供了有效的美国药典、欧洲药典和英国药典一级标准的多重可追溯性。

其他说明

该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

要查看该材料的分析证书示例，请在下面的栏位中输入LRAB3715。这只是一个示例证书，可能不是您收到的批次。

C1650000

硫酸氯喹, European Pharmacopoeia (EP) Reference Standard

1118328

4,7-二氯喹啉, United States Pharmacopeia (USP) Reference Standard

1118361

1118350

1118394

1118000

磷酸氯喹, United States Pharmacopeia (USP) Reference Standard

PHR2438

4,7-二氯喹啉, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2933

象形图

GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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分析证书(COA)

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