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Merck
CN

PHR1181

Supelco

昂丹司琼杂质F

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

2-甲基咪唑, 2-甲基-1,3-氮杂茂

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About This Item

经验公式(希尔记法):
C4H6N2
CAS号:
分子量:
82.10
Beilstein:
1368
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to Ph. Eur. Y0001320

蒸汽压

<1 mmHg ( 0 °C)

API类

ondansetron

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

bp

267-268 °C (lit.)

mp

142-143 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

Cc1ncc[nH]1

InChI

1S/C4H6N2/c1-4-5-2-3-6-4/h2-3H,1H3,(H,5,6)

InChI key

LXBGSDVWAMZHDD-UHFFFAOYSA-N

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA9000 in the slot below. This is an example certificate only and may not be the lot that you receive.

相关产品

产品编号
说明
价格

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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P C Chan et al.
Archives of toxicology, 82(6), 399-412 (2007-10-10)
2-Methylimidazole (2MI) has been identified as a by-product of fermentation and is detected in foods and mainstream and side-stream tobacco smoke. It is used in the manufacture of pharmaceuticals, photographic chemicals, dyes and pigments, agricultural chemicals, and rubber. Carcinogenicity studies
Jerry D Johnson et al.
Journal of toxicology and environmental health. Part A, 65(12), 869-879 (2002-06-25)
The toxicokinetics of 2-methylimidazole (2-MI) were studied in male and female Fischer 344 rats after a single iv dose of 10 mg/kg or gavage dose of 25, 50, or 100 mg/kg. The 2-MI was formulated in 0.05 M phosphate-buffered saline
M van Gastel et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 4(3), 257-265 (1999-08-10)
Frozen solutions of the azurin mutant His117Gly in the presence of excess of methyl-substituted imidazoles have been investigated by electron spin-echo envelope modulation (ESEEM) spectroscopy at 9 GHz. The addition of imidazole is known to reconstitute a blue-copper site and
Janosch Cravillon et al.
Angewandte Chemie (International ed. in English), 50(35), 8067-8071 (2011-07-13)
Prenucleation clusters: in situ synchrotron X-ray scattering with a one-second time resolution revealed the occurrence of nano-sized clusters during the nucleation and early growth of nanocrystals of a zeolitic imidazolate framework (ZIF). The complex crystallization process exhibits similarities with crystallization processes
Wenxiang Cao et al.
Biochemistry, 43(22), 7017-7027 (2004-06-02)
We use laser flash photolysis and time-resolved Raman spectroscopy of CO-bound heme complexes to study proximal and distal influences on ligand rebinding kinetics. We report kinetics of CO rebinding to microperoxidase (MP) and 2-methylimidazole ligated Fe protoporphyrin IX in the

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