PHR1165
萘普生 钠
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
(S)-6-甲氧基-α-甲基-2-萘乙酸 钠盐
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C14H13NaO3
化学文摘社编号:
分子量:
252.24
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
247-486-2
MDL number:
产品名称
萘普生 钠, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
CDBRNDSHEYLDJV-FVGYRXGTSA-M
InChI
1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
SMILES string
[Na+].COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1457403
API family
naproxen
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
Gene Information
human ... PTGS1(5742), PTGS2(5743)
正在寻找类似产品? 访问 产品对比指南
Biochem/physiol Actions
环加氧酶（前列腺素 H 合成酶 1 和 2）抑制剂。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Application
Naproxen sodium may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and combined dosage forms by chromatographic and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Naproxen sodium (NS) is a sodium salt of propionic acid derivative and demonstrates analgesic, anti-pyretic, and anti-inflammatory properties. It exhibits efficiency in being used as an indomethacin in the treatment of acute musculoskeletal disorders. It belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDS) and acts by inhibiting the activity of both the cyclooxygenase enzymes, COX-1 & COX-2 and further blocking the synthesis of certain prostaglandins. It is administered in the treatment of ankylosing spondylitis, osteoarthritis, rheumatoid disorders, acute gout, mild to moderate pain, tendonitis, bursitis, dysmenorrhea, fever, and migraine headache. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7178 in the slot below. This is an example certificate only and may not be the lot that you receive.
Values of analytes vary lot to lot.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 1A
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Rapid simultaneous determination of sumatriptan succinate and naproxen sodium in combined tablets by validated ultra performance liquid chromatographic method
Reddy YR, et al.
Journal of Analytical and Bioanalytical Techniques , 2(3), 1-6 (2011)
Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain
Polat O, et al.
The Angle Orthodontist, 75(5), 791-796 (2005)
Simultaneous determination of naproxen sodium and acetaminophen in fixed-dose combinations formulations by first-order derivative spectroscopy: application to dissolution studies
Medina JR, et al.
International Journal of Pharmacy and Pharmaceutical Sciences, 7(3), 183-188 (2015)
Naproxen sodium, diflunisal, and placebo in the treatment of chronic back pain.
Berry H, et al.
Annals of the Rheumatic Diseases, 41(2), 129-132 (1982)
Validated HPTLC method for simultaneous quantitation of domperidone maleate and naproxen sodium in bulk drug and formulation
Pawar SM, et al.
Eurasian Journal of Analytical Chemistry, 5(3), 284-292 (2010)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持