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PHR1031

Supelco

α-生育酚

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

(±)-α-生育酚, DL-全-rac-α-生育酚, 维生素E

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About This Item

经验公式（希尔记法）:
C29H50O2
CAS号:
10191-41-0
分子量:
430.71
Beilstein:
94012
EC 号:
233-466-0
MDL编号:
MFCD00006848
UNSPSC代码:
41116107
eCl@ss:
34058016
PubChem化学物质编号:
329823061
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 882
traceable to Ph. Eur. T1550000
traceable to USP 1667600

API类

tocopherol

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

密度

0.950 g/mL at 20 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

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相关类别

一般描述

α-生育酚是强大的生物抗氧化剂，是维生素E在人体中最活跃的形式。
用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

应用

α-生育酚可作为药物参考标准品，使用流动注射化学发光技术定量药物制剂中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

这些二级标准品可追溯至USP、EP（PhEur）和BP一级标准品。

其他说明

该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

想要查看本品的分析证书示例，请在下框中输入LRAB3718。这只是一个示例证书，可能与您收到的批次不符。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H317

危险分类

Skin Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 1

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number

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Simultaneous determination of retinol and alpha-tocopherol in serum or plasma by liquid chromatography
Catignani LG and Bieri GJ
Clinical Chemistry, 29, 708-712 (1983)
Sarwat Jahan et al.
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Parkinson's disease (PD) is a neurodegenerative disorder for which environmental factors influence disease risk and may act via an epigenetic mechanism. The microtubule-associated protein tau (MAPT) is a susceptibility gene for idiopathic PD. Methylation levels were determined by pyrosequencing of
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The effect of climate warming on the reproductive success of ectothermic animals is currently a subject of major conservation concern. However, for many threatened species, we still know surprisingly little about the extent of naturally occurring adaptive variation in heat-tolerance.
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实验方案

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

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