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Merck
CN

PHR1031

α-生育酚

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

(±)-α-生育酚, DL-全-rac-α-生育酚, 维生素E

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关于此项目

经验公式(希尔记法):
C29H50O2
化学文摘社编号:
分子量:
430.71
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
34058016
UNSPSC Code:
41116107
EC Number:
233-466-0
MDL number:
Beilstein/REAXYS Number:
94012
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产品名称

α-生育酚, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. T1550000
traceable to USP 1667600

API family

tocopherol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

density

0.950 g/mL at 20 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

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Analysis Note

这些二级标准品可追溯至USP、EP(PhEur)和BP一级标准品。

Application

α-生育酚可作为药物参考标准品,使用流动注射化学发光技术定量药物制剂中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

General description

α-生育酚是强大的生物抗氧化剂,是维生素E在人体中最活跃的形式。
用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

Other Notes

想要查看本品的分析证书示例,请在下框中输入LRAB3718。这只是一个示例证书,可能与您收到的批次不符。
该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

存储类别

10 - Combustible liquids

wgk

WGK 1


分析证书(COA)

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Simultaneous determination of retinol and alpha-tocopherol in serum or plasma by liquid chromatography
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Clinical Chemistry, 29, 708-712 (1983)
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实验方案

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

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