等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to BP 766
traceable to Ph. Eur. C0100000
traceable to USP 1085003
API类
dimenhydrinate, caffeine, pentoxifylline
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
234-236.5 °C (lit.)
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-30°C
SMILES字符串
CN1C(=O)N(C)c2ncn(C)c2C1=O
InChI
1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
InChI key
RYYVLZVUVIJVGH-UHFFFAOYSA-N
基因信息
human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140)
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一般描述
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Caffeine is an N-methyl derivative of xanthine and is involved in gastric acid secretion, diuresis, and stimulation of the central nervous system.
应用
Caffeine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, blood plasma, food, drinks, and herbal products by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAB7780 in the slot below. This is an example certificate only and may not be the lot that you receive.
推荐产品
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
相关产品
产品编号
说明
价格
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Simultaneous voltammetric determination of paracetamol and caffeine in pharmaceutical formulations using a boron-doped diamond electrode.
Lourenc?o BC
Talanta, 78(3), 748-752 (2009)
Simultaneous HPLC determination of caffeine, theobromine, and theophylline in food, drinks, and herbal products.
Srdjenovic B, et al.
Journal of Chromatographic Science, 46(2), 144-149 (2008)
Simultaneous determination of caffeine and non-steroidal anti-inflammatory drugs in pharmaceutical formulations and blood plasma by reversed-phase HPLC from linear gradient elution.
Mart?n MJ, et al.
Talanta, 49(2), 453-459 (1999)
Markus Fehrholz et al.
American journal of physiology. Lung cellular and molecular physiology, 306(1), L101-L109 (2013-10-29)
Factors positively influencing surfactant homeostasis in general and surfactant protein B (SP-B) expression in particular are considered of clinical importance regarding an improvement of lung function in preterm infants. The objective of this study was to identify effects of physiological
Jonathan M Hodgson et al.
The American journal of clinical nutrition, 97(5), 943-950 (2013-04-05)
Measures of blood pressure variation have been associated with cardiovascular disease and related outcomes. The regular consumption of black tea can lower blood pressure, but its effects on blood pressure variation have yet to be investigated. We aimed to assess
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