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Merck
CN

P4347

Sigma-Aldrich

丙二醇

meets USP testing specifications

别名:

1,2-丙二醇, 1,2-PDO, 丙烷-1,2-二醇, 甲基乙基乙二醇, 丙二醇

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About This Item

线性分子式:
CH3CH(OH)CH2OH
CAS号:
分子量:
76.09
Beilstein:
1340498
EC 号:
MDL编号:
UNSPSC代码:
12161700
PubChem化学物质编号:
NACRES:
NA.25

Agency

USP/NF
meets USP testing specifications

质量水平

蒸汽密度

2.62 (vs air)

蒸汽压

0.08 mmHg ( 20 °C)

自燃温度

779 °F

expl. lim.

12.5 %

折射率

n20/D 1.432 (lit.)

bp

187 °C (lit.)

mp

−60 °C (lit.)

密度

1.036 g/mL at 25 °C (lit.)

应用

general analytical
pharmaceutical (small molecule)
sample preparation

SMILES字符串

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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一般描述

丙二醇是一种低分子量的脂肪醇,是生物和药物配方研究中的重要溶剂。它与水和多种有机化合物的出色混溶性,加上低凝固点、低蒸汽压和无毒性,使其成为各种研究应用的首选材料,特别是在敏感的生物测定和药物制剂中。

除了溶剂能力,丙二醇在药物配方中是出色的赋形剂,提高了治疗分子和药物添加剂的溶解度和稳定性。这一特性在赋形剂和给药研究中被证明是不可或缺的,有助于开发更有效、更稳定的药物。在生化和生理研究中,丙二醇作为一种有效的冷冻保护剂,保护细胞和组织免受冷冻引起的损伤。它的应用扩展到药物吸收、代谢和分布研究,为研究人员提供了一个关键的工具来破译药物在体内的复杂旅程。

丙二醇的多功能性延伸到分子生物学,特别是在聚合酶链反应 (PCR) 中,可保护 DNA 和 RNA 链,确保可靠和可重复的结果。研究表明,它具有长时间稳定 DNA 的特殊能力,使其成为遗传和基因组分析中长期保存样本的重要组成部分。在制药工业中,丙二醇作为溶剂和萃取介质被广泛使用,在药物开发研究中起着举足轻重的作用,促进了生物活性化合物的高效提取和纯化。

应用

丙二醇已用于:
  • 去除斑马鱼幼体中多余的油红 O 色斑
  • 制备藻酸盐水凝胶
  • 溶解雄甾烯酮
  • 用于计算机断层扫描中锥束扫描仪的校准

特点和优势

  • 用途广泛,适应各种实验室和研究应用
  • 符合 USP 检测规范

其他说明

如需了解生化试剂系列的更多信息,请填写此表

可比产品

产品编号
说明
价格

WGK

WGK 1

闪点(°F)

219.2 °F

闪点(°C)

104 °C

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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