82281
1,2-丙二醇
tested according to Ph. Eur.
别名:
丙二醇
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关于此项目
线性分子式:
CH3CH(OH)CH2OH
化学文摘社编号:
分子量:
76.09
UNSPSC Code:
12352200
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-338-0
Beilstein/REAXYS Number:
1340498
MDL number:
产品名称
1,2-丙二醇, tested according to Ph. Eur.
InChI key
DNIAPMSPPWPWGF-UHFFFAOYSA-N
InChI
1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
SMILES string
CC(O)CO
agency
USP/NF
tested according to Ph. Eur.
vapor density
2.62 (vs air)
vapor pressure
0.08 mmHg ( 20 °C)
form
viscous liquid
autoignition temp.
779 °F
expl. lim.
12.5 %
refractive index
n20/D 1.432 (lit.)
bp
187 °C (lit.)
mp
−60 °C (lit.)
density
1.036 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
Quality Level
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
219.2 °F - closed cup
flash_point_c
104 °C - closed cup
ppe
Eyeshields, Gloves
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To achieve a therapeutical effect of the anti-Parkinson's drug R-apomorphine via iontophoresis delivery, enhancement strategies in vitro were explored using three structurally related enhancers, lauric acid (LA), dodecyltrimethylammonium bromide (DTAB) and Laureth-3 oxyethylene ether (C(12)EO(3)). Human stratum corneum and shed
H K Vaddi et al.
Journal of pharmaceutical sciences, 91(7), 1639-1651 (2002-07-13)
The respective alcoholic terpenes carvacrol, linalool, and alpha-terpineol were used at 5% w/v in propylene glycol (PG) to increase the in vitro permeation of haloperidol (HP) through human skin. The possible enhancement mechanism was then elucidated with HP-stratum corneum (SC)
R S Rajasenan et al.
Toxicology and applied pharmacology, 135(1), 89-99 (1995-11-01)
Engrafting components of human immune systems in severe combined immunodeficient (SCID) mice has been utilized to investigate the pathogenesis of several human autoimmune diseases and may provide a model for studying idiosyncratic drug toxicity. The purpose of this investigation was
G A Reichard et al.
Diabetes, 35(6), 668-674 (1986-06-01)
Plasma acetone turnover rates were measured with the primed continuous infusion of 2-[14C]acetone in patients with moderate to severe diabetic ketoacidosis. Plasma acetone turnover rates ranged from 1.52 to 15.9 mumol X kg-1 X min-1 (108-1038 mumol X 1.73 m-2
C Fernandez et al.
Journal of pharmaceutical and biomedical analysis, 24(1), 155-165 (2000-12-07)
The aim of this study was to determine the skin penetration of benzophenone-3 in vitro and in vivo in order to investigate a possible influence of formulation. Six different vehicles, three solvents and three different emulsion types were evaluated in
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