product name
聚(乙二醇), BioXtra, average mol wt 3,350, powder
产品线
BioXtra
质量水平
形式
powder
分子量
average mol wt 3,350
杂质
≤0.01% Phosphorus (P)
≤0.1% Insoluble matter
溶解性
water: soluble (PEG is soluble in water approximately 670 mg/ml, 20 °C)
密度
1.0962 g/mL at 60 °C
1.0764 g/mL at 80 °C
痕量阴离子
chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
痕量阳离子
Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%
Ω端
hydroxyl
α端
hydroxyl
SMILES字符串
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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一般描述
聚乙二醇(PEG)是一种亲水性聚合物。它可以通过环氧乙烷的阴离子开环聚合反应而进行合成,产生不同的分子量和端基。当交联成网络时,PEG可具有高含水量,形成“水凝胶”。聚乙二醇(PEG)不会引发免疫反应,是一种理想的生物学应用材料。
应用
聚乙二醇(PEG)可与非离子表面活性剂吐温80共同官能化修饰磁性纳米颗粒。聚乙二醇官能化可增强磁纳米颗粒的生物相容性。还能降低表面电荷,维持纳米颗粒的磁性。
聚乙二醇可用作药物最终剂型的外部包衣,为原料药提供防潮保护。例如,drop printing(液滴打印)技术可使聚乙二醇包覆在萘普生固体分散体上。PEG包衣可保护固体分散体,避免潮湿导致的结晶加快,并增强稳定性。
以聚乙二醇作为有机改性剂,通过溶胶-凝胶技术可制备纳米结构的羟磷灰石(HAP)。聚乙二醇可影响羟磷灰石形态。高温下,柔性更高的聚乙二醇分子形成更大的羟基磷灰石片。低温下,柔性较低的聚乙二醇胶体形成纳米结构的羟磷灰石。
聚乙二醇还可作为泻药使用。
聚乙二醇可用作药物最终剂型的外部包衣,为原料药提供防潮保护。例如,drop printing(液滴打印)技术可使聚乙二醇包覆在萘普生固体分散体上。PEG包衣可保护固体分散体,避免潮湿导致的结晶加快,并增强稳定性。
以聚乙二醇作为有机改性剂,通过溶胶-凝胶技术可制备纳米结构的羟磷灰石(HAP)。聚乙二醇可影响羟磷灰石形态。高温下,柔性更高的聚乙二醇分子形成更大的羟基磷灰石片。低温下,柔性较低的聚乙二醇胶体形成纳米结构的羟磷灰石。
聚乙二醇还可作为泻药使用。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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