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Merck
CN

P4338

Sigma-Aldrich

聚(乙二醇)

average MN 3,350, hydroxyl, BioXtra

别名:

PEG

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About This Item

线性分子式:
H(OCH2CH2)nOH
CAS号:
MDL编号:
UNSPSC代码:
12352104
PubChem化学物质编号:
NACRES:
NA.23

product name

聚(乙二醇), BioXtra, average mol wt 3,350, powder

产品线

BioXtra

质量水平

形式

powder

分子量

average mol wt 3,350

杂质

≤0.01% Phosphorus (P)
≤0.1% Insoluble matter

溶解性

water: soluble (PEG is soluble in water approximately 670 mg/ml, 20 °C)

密度

1.0962 g/mL at 60 °C
1.0764 g/mL at 80 °C

痕量阴离子

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

痕量阳离子

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

Ω端

hydroxyl

α端

hydroxyl

SMILES字符串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般描述

聚乙二醇(PEG)是一种亲水性聚合物。它可以通过环氧乙烷的阴离子开环聚合反应而进行合成,产生不同的分子量和端基。当交联成网络时,PEG可具有高含水量,形成“水凝胶”。聚乙二醇(PEG)不会引发免疫反应,是一种理想的生物学应用材料。

应用

聚乙二醇(PEG)可与非离子表面活性剂吐温80共同官能化修饰磁性纳米颗粒。聚乙二醇官能化可增强磁纳米颗粒的生物相容性。还能降低表面电荷,维持纳米颗粒的磁性。

聚乙二醇可用作药物最终剂型的外部包衣,为原料药提供防潮保护。例如,drop printing(液滴打印)技术可使聚乙二醇包覆在萘普生固体分散体上。PEG包衣可保护固体分散体,避免潮湿导致的结晶加快,并增强稳定性。

以聚乙二醇作为有机改性剂,通过溶胶-凝胶技术可制备纳米结构的羟磷灰石(HAP)。聚乙二醇可影响羟磷灰石形态。高温下,柔性更高的聚乙二醇分子形成更大的羟基磷灰石片。低温下,柔性较低的聚乙二醇胶体形成纳米结构的羟磷灰石。

聚乙二醇还可作为泻药使用。

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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