推荐产品
产品名称
聚（乙二醇）, BioXtra, average mol wt 3,350, powder
产品线
BioXtra
质量水平
表单
powder
分子量
average mol wt 3,350
杂质
≤0.01% Phosphorus (P)
≤0.1% Insoluble matter
溶解性
water: soluble (PEG is soluble in water approximately 670 mg/ml, 20 °C)
密度
1.0962 g/mL at 60 °C
1.0764 g/mL at 80 °C
痕量阴离子
chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
痕量阳离子
Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%
Ω端
hydroxyl
α端
hydroxyl
SMILES字符串
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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相关类别
一般描述
聚乙二醇（PEG）是一种亲水性聚合物。它可以通过环氧乙烷的阴离子开环聚合反应而进行合成，产生不同的分子量和端基。当交联成网络时，PEG可具有高含水量，形成“水凝胶”。聚乙二醇（PEG）不会引发免疫反应，是一种理想的生物学应用材料。
应用
聚乙二醇(PEG)可与非离子表面活性剂吐温80共同官能化修饰磁性纳米颗粒。聚乙二醇官能化可增强磁纳米颗粒的生物相容性。还能降低表面电荷，维持纳米颗粒的磁性。
聚乙二醇可用作药物最终剂型的外部包衣，为原料药提供防潮保护。例如，drop printing（液滴打印）技术可使聚乙二醇包覆在萘普生固体分散体上。PEG包衣可保护固体分散体，避免潮湿导致的结晶加快，并增强稳定性。
以聚乙二醇作为有机改性剂，通过溶胶-凝胶技术可制备纳米结构的羟磷灰石(HAP)。聚乙二醇可影响羟磷灰石形态。高温下，柔性更高的聚乙二醇分子形成更大的羟基磷灰石片。低温下，柔性较低的聚乙二醇胶体形成纳米结构的羟磷灰石。
聚乙二醇还可作为泻药使用。
聚乙二醇可用作药物最终剂型的外部包衣，为原料药提供防潮保护。例如，drop printing（液滴打印）技术可使聚乙二醇包覆在萘普生固体分散体上。PEG包衣可保护固体分散体，避免潮湿导致的结晶加快，并增强稳定性。
以聚乙二醇作为有机改性剂，通过溶胶-凝胶技术可制备纳米结构的羟磷灰石(HAP)。聚乙二醇可影响羟磷灰石形态。高温下，柔性更高的聚乙二醇分子形成更大的羟基磷灰石片。低温下，柔性较低的聚乙二醇胶体形成纳米结构的羟磷灰石。
聚乙二醇还可作为泻药使用。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
M A Thomson et al.
Archives of disease in childhood, 92(11), 996-1000 (2007-07-13)
To assess the efficacy and safety of polyethylene glycol 3350 plus electrolytes (PEG+E) for the treatment of chronic constipation in children. Randomised, double blind, placebo controlled crossover trial, with two 2-week treatment periods separated by a 2-week placebo washout. Six
Dafne Campigli Di Giammartino et al.
Nature cell biology, 21(10), 1179-1190 (2019-09-25)
Cell fate transitions are accompanied by global transcriptional, epigenetic and topological changes driven by transcription factors, as is exemplified by reprogramming somatic cells to pluripotent stem cells through the expression of OCT4, KLF4, SOX2 and cMYC. How transcription factors orchestrate
Maria Paz Zafra et al.
Nature biotechnology, 36(9), 888-893 (2018-07-04)
CRISPR base editing enables the creation of targeted single-base conversions without generating double-stranded breaks. However, the efficiency of current base editors is very low in many cell types. We reengineered the sequences of BE3, BE4Gam, and xBE3 by codon optimization
Jacky Chow et al.
mSphere, 4(2) (2019-03-08)
Many fungal species, including pathogens, undergo a morphogenetic response called filamentous growth, where cells differentiate into a specialized cell type to promote nutrient foraging and surface colonization. Despite the fact that filamentous growth is required for virulence in some plant
Calla B Shubin et al.
eLife, 9 (2020-07-01)
To examine the established link between DNA replication and telomere length, we tested whether firing of telomeric origins would cause telomere lengthening. We found that RIF1 mutants that block Protein Phosphatase 1 (PP1) binding activated telomeric origins but did not
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