P1061
盐酸普罗地芬 盐酸盐
analytical standard, ≥95%
别名:
α-苯基-α-丙基苯乙酸-2-(二乙氨)乙酯, N,N-二乙基氨基乙基 2,2-二苯基戊酸酯, SKF-525A
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关于此项目
经验公式（希尔记法）:
C23H31NO2 · HCl
化学文摘社编号:
分子量:
389.96
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
盐酸普罗地芬 盐酸盐, analytical standard, ≥95%
InChI
1S/C23H31NO2.ClH/c1-4-17-23(20-13-9-7-10-14-20,21-15-11-8-12-16-21)22(25)26-19-18-24(5-2)6-3;/h7-16H,4-6,17-19H2,1-3H3;1H
SMILES string
Cl.CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2
InChI key
FHIKZROVIDCMJA-UHFFFAOYSA-N
grade
analytical standard
assay
≥95%
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
122-123 °C
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
Quality Level
Gene Information
human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
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Application
有关合适的仪器技术的更多信息，请参阅产品的分析证书。如需进一步支持，请联系技术服务。
盐酸普瑞迪芬可用作内标，用气相色谱-质谱联用（GC-MS）测定人尿样中的 O-去甲基曲马多、曲马多和 N-去甲基曲马多镇痛剂。
Biochem/physiol Actions
阻断格列本脲敏感 K+ 通道。抑制神经元性一氧化氮合成酶和细胞色素 P450
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Amber Woodard et al.
AIMS neuroscience, 6(1), 25-42 (2020-04-29)
Neuronal nitric oxide (nNO) has been shown to affect motor function in the brain. Specifically, nNO acts in part through regulation of dopamine (DA) release, transporter function, and the elicitation of neuroprotection/neurodegeneration of neurons in conditions such as Parkinson's disease
David Fuchs et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(4), 158611-158611 (2020-01-10)
Trihydroxyoctadecenoic acids (TriHOMEs) are linoleic acid-derived lipid mediators reported to be dysregulated in obstructive lung disease. In contrast to many other oxylipins, TriHOME biosynthesis in humans is still poorly understood. The association of TriHOMEs with inflammation prompted the current investigation
Daniele Giovanni Ghiglioni et al.
Pharmaceutics, 12(4) (2020-04-25)
In this study, a sensitive quantitative method based on high performance liquid chromatography combined with high-resolution mass spectrometry, Q ExactiveTM-Orbitrap® was set up and applied for the determination of the immunosuppressor agents cyclosporine A and tacrolimus in novel ethanol-free ophthalmic
Simultaneous determination of tramadol, O-desmethyltramadol and N-desmethyltramadol in human urine by gas chromatography?mass spectrometry
El-Sayed Y A-A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 926, 9-15 (2013)
Joseph A Crifasi et al.
Journal of analytical toxicology, 30(8), 581-592 (2006-11-30)
Stir bar sorptive extraction is an innovative sample extraction technique that can be used to process blood, urine, and tissue samples for routine drug screening in the forensic toxicology laboratory. The Gerstel Twister desorption unit (TDU) system is a multifunctional
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