等级
certified reference material
质量水平
形式
liquid
包装
pkg of 5 x 1 mL
制造商/商品名称
NIST®
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
mass spectrometry (MS): suitable
应用
clinical research
格式
matrix material
一般描述
SRM 1950 is designed to represent “normal” human plasma.
It was developed in a collaboration between the National Institute of Standards and Technology (NIST) and the National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Analyses for value assignment were performed by NIST and the Centers for Disease Control and Prevention (CDC) (Atlanta, GA). All certified and reference values, with the exception of vitamin D-binding protein, are based on the agreement between the results from NIST methods and from the CDC, where available. The reference value for vitamin D-binding protein is based on the agreement between the results from a NIST method and the University of Washington method.
SRM 1950 _SDS
SRM 1950_CERT
It was developed in a collaboration between the National Institute of Standards and Technology (NIST) and the National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Analyses for value assignment were performed by NIST and the Centers for Disease Control and Prevention (CDC) (Atlanta, GA). All certified and reference values, with the exception of vitamin D-binding protein, are based on the agreement between the results from NIST methods and from the CDC, where available. The reference value for vitamin D-binding protein is based on the agreement between the results from a NIST method and the University of Washington method.
SRM 1950 _SDS
SRM 1950_CERT
应用
This Standard Reference Material (SRM) is intended primarily for the validation of methods for determining metabolites such as fatty acids, electrolytes, vitamins, hormones, and amino acids in human plasma and similar materials. This SRM can also be used for comparison of measurement technologies used in metabolomic studies and for quality assurance when assigning values to in-house reference materials.
The standard has been used:
The standard has been used:
- to determine the accuracy of vitamin D in human serum by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
- to determine the unbound free fatty acid profile of human plasma
- to determine the C24 bile acids in human serum and urine samples by liquid chromatography-mass spectrometry (LC-MS) method
特点和优势
- A unit of SRM 1950 consists of five vials, each containing approximately 1.0 mL of plasma
- The associated uncertainties are expressed at the 95 %level of confidence
- Information on product description, disposal, and transportation is available in the accompanying MSDS
- The enclosed NIST certificate contains details on the expiry date, warning to users, instructions for right storage and use, preparation, and analysis of the RM
法律信息
NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology
WGK
WGK 3
法规信息
高风险级别生物产品--人源产品
Quantification of vitamin D and 25-hydroxyvitamin D in soft tissues by liquid chromatography-tandem mass spectrometry
Lipkie TE, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 932, 6-11 (2013)
Unbound free fatty acid profiles in human plasma and the unexpected absence of unbound palmitoleate
Huber AH and Kleinfeld AM
Journal of Lipid Research, 58(3), 578-585 (2017)
Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids
Zhu P, et al.
Analytical and Bioanalytical Chemistry, 410(21), 5287-5300 (2018)
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