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About This Item
经验公式（希尔记法）:
C17H15NO3
CAS号:
分子量:
281.31
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
analytical standard
质量水平
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
CC(C(O)=O)c1ccc(cc1)N2Cc3ccccc3C2=O
InChI
1S/C17H15NO3/c1-11(17(20)21)12-6-8-14(9-7-12)18-10-13-4-2-3-5-15(13)16(18)19/h2-9,11H,10H2,1H3,(H,20,21)
InChI key
RJMIEHBSYVWVIN-UHFFFAOYSA-N
基因信息
human ... IL8RA(3577) , PTGS1(5742) , PTGS2(5743)
应用
Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities. Its mode of action involves the inhibition of prostaglandin synthesis.
Indoprofen may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.
Indoprofen may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.
Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Carc. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Mitchell R Lunn et al.
Chemistry & biology, 11(11), 1489-1493 (2004-11-24)
Most patients with the pediatric neurodegenerative disease spinal muscular atrophy have a homozygous deletion of the survival motor neuron 1 (SMN1) gene, but retain one or more copies of the closely related SMN2 gene. The SMN2 gene encodes the same
D Siebler et al.
Arzneimittel-Forschung, 39(6), 659-660 (1989-06-01)
Binding of Racemic Indoprofen and its Enantiomers to Human Serum Albumin. The binding to 2% and 4% human serum albumin (HSA) of (+/-)-indoprofen, (-)-indoprofen, and (+)-indoprofen was examined applying a modified ultrafiltration process. The binding properties to HSA were characterized
B Lund et al.
British journal of clinical pharmacology, 22(6), 721-724 (1986-12-01)
Multiple dosing four times daily for 7 days of indoprofen 200 mg, a non-steroidal anti-inflammatory drug with a short half-life (t1/2), revealed drug accumulation in eight elderly subjects. This indicates a substantially longer t1/2 (11 h) than that reported in
Determination of the enantiomers of indoprofen in blood plasma by high-performance liquid chromatography after rapid derivatization by means of ethyl chloroformate
Bjorkman S
Journal of Chromatography. B, Biomedical Applications, 339(2), 339-346 (1985)
Nicholas J Lawrence et al.
The Journal of organic chemistry, 67(2), 457-464 (2002-01-19)
The intermediate anion derived from the vicarious nucleophilic substitution (VNS) of hydrogen reacts with a series of alkyl halides to generate the corresponding alpha-alkylated conventional VNS product in a one-pot process. This one-pot VNS-alkylation reaction offers a convenient route to
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