所有图片(1)
别名:
α-甲基-4-(2-甲基丙基)苯乙酸
线性分子式:
C13H17O2Na
CAS号:
分子量:
228.26
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
analytical standard
质量水平
检测方案
≥98% (GC)
技术
HPLC: suitable
gas chromatography (GC): suitable
溶解性
H2O: 100 mg/mL, clear to slightly hazy
应用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
SMILES字符串
[Na+].CC(C)Cc1ccc(cc1)C(C)C([O-])=O
InChI
1S/C13H18O2.Na/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;/h4-7,9-10H,8H2,1-3H3,(H,14,15);/q;+1/p-1
InChI key
PTTPUWGBPLLBKW-UHFFFAOYSA-M
基因信息
human ... PTGS1(5742) , PTGS2(5743)
一般描述
布洛芬属于非固醇类消炎药类， 广泛用于治疗轻到中度疼痛和严重的关节炎。
应用
布洛芬可用作分析参考标准品，用于通过高效液相色谱（HPLC）定量检测废水中的分析物。
布洛芬钠盐可用作模型药物，通过布洛芬与生物相容性水滑石化合物之间的离子交换反应来研究插层机理。
有关合适的仪器技术的更多信息，请参阅产品的分析证书。如需进一步支持，请联系技术服务。
生化/生理作用
环加氧酶 (COX) 抑制剂，对 COX-1 的活性高于对 COX-2 的活性。
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WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Abegaz Tizazu Andrgie et al.
Polymers, 12(11) (2020-11-12)
Hydrogels have been investigated as ideal biomaterials for wound treatment owing to their ability to form a highly moist environment which accelerates cell migration and tissue regeneration for prompt wound healing. They can also be used as a drug carrier
Mixed supramolecular hemimicelles aggregates and magnetic carrier technology for solid phase extraction of ibuprofen in environmental samples prior to its HPLC-UV determination
Beiraghi A, et al.
Chemical Engineering Science, 108(3), 103-110 (2014)
Emanuele Mauri et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 146, 143-149 (2019-11-15)
Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug (NSAID) commonly used in the treatment of pain, fever and inflammation. However, the administration of IBU in its free carboxylic acid form is strongly dependent on its limited solubility in aqueous solution. This
Determination of non-steroidal anti-inflammatory drugs in wastewaters by magnetic matrix solid phase dispersion?HPLC
Aguilar-Arteaga.K, et al.
Talanta, 80(3), 1152-1157 (2010)
Intercalation compounds of hydrotalcite-like anionic clays with antiinflammatory agents?I. Intercalation and in vitro release of ibuprofen
Ambrogi V, et al.
International Journal of Pharma Research & Review, 220, 23-32 (2001)
Chromatograms
suitable for GCapplication for HPLC我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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