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Merck
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D5545

Sigma-Aldrich

DL-二硫苏糖醇

BioXtra, ≥99.0% (titration)

别名:

1,4-二巯基苏糖醇, DTT, 克莱兰氏试剂

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1 VIAL
¥5,930.08

¥5,930.08

预计发货时间2025年4月14日详情

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1 VIAL
¥5,930.08

About This Item

线性分子式:
HSCH2CH(OH)CH(OH)CH2SH
CAS号:
3483-12-3
分子量:
154.25
Beilstein:
1719757
EC 号:
222-468-7
MDL编号:
MFCD00004877
UNSPSC代码:
12352201
PubChem化学物质编号:
24893941
NACRES:
NA.21

¥5,930.08

预计发货时间2025年4月14日详情

获取大包装报价

产品线

BioXtra

质量水平

200

方案

≥99.0% (titration)

表单

powder

反应适用性

reagent type: reductant

杂质

Insoluble matter, passes filter test
≤0.3% 4,5-dihydroxy-1,2-dithiane

pH值（酸碱度）

4.0-6.0 (20-25 °C, 0.1 m in H2O)

mp

41-44 °C (lit.)

溶解性

H2O: 0.1 M, clear, colorless

痕量阴离子

sulfate (SO42-): ≤0.005%

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PYR0MATIL6

PyroMAT® Interleukin IL-6 standard

SILu™Prot IL6 Interleukin 6 human recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C- and 15N-labeled

MSST0017

SILu™Prot IL6 Interleukin 6 human

Rat Interleukin-6 ELISA Kit for for cell lysate and tissue lysate

RAB0312

Rat Interleukin-6 ELISA Kit

Mouse IL-6 ELISA Kit for serum, plasma and cell culture supernatant

RAB0308

Mouse IL-6 ELISA Kit

Quality Level

400

Quality Level

200

Quality Level

-

Quality Level

-

packaging

pkg of 1 vial

packaging

-

packaging

kit of 96 wells (12 strips x 8 wells)

packaging

kit of 96 wells (12 strips x 8 wells)

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

ambient

shipped in

-

shipped in

wet ice

shipped in

wet ice

agency

EP Chapter 2.6.30

agency

-

agency

-

agency

-

应用

用于将 −SH 基保持在还原态的绝佳试剂；定量还原二硫化物。在 SDS-PAGE 前，DTT 在样品缓冲液中可有效还原蛋白二硫键。DTT 还可用于还原交联剂 N,N′-双(丙烯酰)胱胺的二硫键桥以分解聚丙烯酰胺凝胶基质。DTT 的刺激性和毒性都低于 2-巯基乙醇。通常，使用 DTT (100mM) 所需的浓度是使用 2-巯基乙醇 (5% v/v, 700mM) 的浓度的七分之一。

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险声明

H302,H315,H318

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000432437
0000432437
0000427655
0000427655
0000416535

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Alessio Grimaldi et al.
Communications biology, 3(1), 85-85 (2020-02-27)
Here, we developed an unbiased, functional target-discovery platform to identify immunogenic proteins from primary non-small cell lung cancer (NSCLC) cells that had been induced to apoptosis by cisplatin (CDDP) treatment in vitro, as compared with their live counterparts. Among the
Carl M Sellgren et al.
Nature neuroscience, 22(3), 374-385 (2019-02-06)
Synapse density is reduced in postmortem cortical tissue from schizophrenia patients, which is suggestive of increased synapse elimination. Using a reprogrammed in vitro model of microglia-mediated synapse engulfment, we demonstrate increased synapse elimination in patient-derived neural cultures and isolated synaptosomes.
Kuang Shen et al.
Cell, 179(6), 1319-1329 (2019-11-11)
mTORC1 controls anabolic and catabolic processes in response to nutrients through the Rag GTPase heterodimer, which is regulated by multiple upstream protein complexes. One such regulator, FLCN-FNIP2, is a GTPase activating protein (GAP) for RagC/D, but despite its important role
Xueqian Liu et al.
The Journal of biological chemistry, 288(10), 7230-7240 (2013-01-25)
In Pichia pastoris, the peroxisomal targeting signal 2 (PTS2)-dependent peroxisomal matrix protein import pathway requires the receptor, Pex7, and its co-receptor Pex20. A conserved lysine (Lys(19)) near the N terminus of Pex20 is required for its polyubiquitination and proteasomal degradation
Jin-Gu Lee et al.
Nature communications, 4, 1568-1568 (2013-03-07)
In eukaryotes, deubiquitinases (DUBs) remove ubiquitin conjugates from diverse substrates, altering their stabilities, localizations or activities. Here we show that many DUBs of the USP and UCH subfamilies can be reversibly inactivated upon oxidation by reactive oxygen species in vitro
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