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等级
anhydrous
质量水平
Agency
USP/NF
meets USP testing specifications
表单
crystalline
powder
mp
234-236.5 °C (lit.)
溶解性
H2O: soluble 18.7 g/L at 16 °C
SMILES字符串
CN1C(=O)N(C)c2ncn(C)c2C1=O
InChI
1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
InChI key
RYYVLZVUVIJVGH-UHFFFAOYSA-N
基因信息
human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140) , PDE4B(5142)
mouse ... Adora2b(11541)
rat ... Adora1(29290) , Adora2a(25369)
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一般描述
Caffeine is a commonly consumed pharmacologically active substance. It is a member of the class of methylxanthines. It is a natural alkaloid found in coffee, cocoa and other plants. Caffeine might be linked to osteoporosis, cardiovascular risk, arrhythmia and gastrointestinal disturbances. Caffeine is used to treat orthostatic hypotension, bronchopulmonary dysplasia and apnea of prematurity (AOP).
应用
Caffeine has been used:
- to functionally disable Ca2+ removal via sarco/endoplasmic reticulum Ca2+ ATPase (SERCA)
- to determine its effects in overcoming excitation-contraction-coupling failure
- to compare its role as a stimulant with guarana
警示用语:
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
13 - Non Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
监管及禁止进口产品
从最新的版本中选择一种:
分析证书(COA)
There and back again: Iterating between population-based modeling and experiments reveals surprising regulation of calcium transients in rat cardiac myocytes
Journal of Molecular and Cellular Cardiology, 96, 38-48 (2016)
Caffeine?s beneficial effect on maximal voluntary strength and activation in uninjured but not injured muscle
International Journal of Sport Nutrition and Exercise Metabolism, 18(6), 639-652 (2008)
Effects of caffeine on human health
Food Additives and Contaminants, 20(1), 1-30 (2003)
Metabolic effects of spices, teas, and caffeine
Physiology & Behavior, 89(1), 85-91 (2006)
Apnea of prematurity: from cause to treatment
European Journal of Pediatrics, 170(9), 1097-1105 (2011)
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