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主要文件

A7250

Sigma-Aldrich

N-乙酰基-L-半胱氨酸

≥99% (TLC)

别名:

LNAC, NAC

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About This Item

线性分子式:
HSCH2CH(NHCOCH3)CO2H
CAS号:
分子量:
163.19
Beilstein:
1724426
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

价格与库存信息目前不能提供

产品名称

N-乙酰基-L-半胱氨酸, Sigma Grade, ≥99% (TLC), powder

等级

Sigma Grade

质量水平

方案

≥99% (TLC)

表单

powder

颜色

white to off-white

mp

106-108 °C (lit.)

溶解性

H2O: 100 mg/mL (with heating)

应用

cell analysis

储存温度

2-8°C

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应用

N-乙酰基-L-半胱氨酸已用于抑制酿酒酵母中氧依赖性羟基脲的敏感性。[1]它还被用作治疗C2C12鼠成肌细胞的抗氧化剂。[2]

生化/生理作用

抗氧化剂和黏液溶解剂(mucolytic agent)。增加细胞池的自由基清除剂。 据报道可防止神经细胞凋亡,但会诱导平滑肌细胞凋亡。抑制HIV复制。可作为微粒体谷胱甘肽转移酶的底物。

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说明
价格

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

13 - Non Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Loss of SOD1 and LYS7 Sensitizes Saccharomyces cerevisiae to Hydroxyurea and DNA Damage Agents and Downregulates MEC1 Pathway Effectors?
    Carole D. Carter
    Journal of Virology, 25(23), 10273-10285 (2005)
    Low levels of lipopolysaccharide modulate mitochondrial oxygen consumption in skeletal muscle
    Madlyn I. Frisard
    Metabolism and Disease, 64(3), 416-427 (2015)
    Carolina Martinez Romão et al.
    Life sciences, 231, 116544-116544 (2019-06-11)
    To investigate the effect of long-term N-acetyl-l-cysteine (NAC) treatment in Wistar rats subjected to renal ischemia and reperfusion (IR) and a chronic high‑sodium diet (HSD). Adult male Wistar rats received an HSD (8.0% NaCl) or a normal‑sodium diet (NSD; 1.3%
    Suzanne M Cloonan et al.
    Journal of medicinal chemistry, 58(11), 4494-4505 (2015-05-12)
    Ruthenium polypyridyl complexes show great promise as new photodynamic therapy (PDT) agents. However, a lack of detailed understanding of their mode of action in cells poses a challenge to their development. We have designed a new Ru(II) PDT candidate that
    Yuval Samuni et al.
    Biochimica et biophysica acta, 1830(8), 4117-4129 (2013-04-27)
    N-acetylcysteine (NAC) has been in clinical practice for several decades. It has been used as a mucolytic agent and for the treatment of numerous disorders including paracetamol intoxication, doxorubicin cardiotoxicity, ischemia-reperfusion cardiac injury, acute respiratory distress syndrome, bronchitis, chemotherapy-induced toxicity

    商品

    Amino Acid Codon Wheel for fast RNA translation. Find which amino acid is translated from your RNA sequence quickly and easily.

    Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

    抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

    Chromatograms

    application for HPLC

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