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Merck
CN

A5131

Sigma-Aldrich

L -精氨酸 单盐酸盐

≥98% (HPLC)

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别名:
(S)-(+)-2-氨基-5-[(氨基亚甲基)氨基]戊酸 单盐酸盐, (S)-(+)-精氨酸 盐酸盐
经验公式(希尔记法):
C6H14N4O2 · HCl
CAS号:
分子量:
210.66
Beilstein:
3631658
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

等级

reagent grade

质量水平

检测方案

≥98% (HPLC)

形式

powder

颜色

white

mp

>235 °C

溶解性

H2O: 50 mg/mL

应用

cell analysis

SMILES字符串

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

InChI key

KWTQSFXGGICVPE-WCCKRBBISA-N

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应用

L-精氨酸单盐酸盐已被用于研究氨基酸在促进果蝇(Drosophila melanogaster)食物消耗中的作用。它还被用于开发大鼠的非侵入性慢性胰腺炎模型。

生化/生理作用

L-精氨酸是一种半必需氨基酸。这种二元氨基酸可作为肌酸酐的前体,是大多数膳食蛋白质的天然成分。
一氧化氮合成酶的底物,可以转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Are solutions of Product No. A5131 (L-Arginine monohydrochloride) autoclavable?

    Arginine is routinely autoclaved as a component of microbial media with no adverse effects; therefore solutions of A5131 L-Arginine monohydrochloride may be autoclaved.

  6. What is the method of preparation process for the A5131 L-Arginine monohydrochloride?

    No animal proteins or products are used in the fermentation process or purification of the L-Arginine.

  7. What are the solubility properties of L-Arginine monohydrochloride (Product No. A5131)?

    L-Arginine monohydrochloride is soluble in water at a concentration of 1M (210 mg/mL).

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Yang Liu et al.
Biochemical and biophysical research communications, 525(3), 620-625 (2020-03-03)
The circadian clock, a biochemical oscillator, plays a fundamental role in health and diseases. Ferroptosis, a type of regulated cell death driven by oxidative stress, is a prominent feature in iron-induced tissue injury. However, whether an impaired circadian clock contributes
J. P. Felix D'Mello
Amino Acids in Human Nutrition and Health (2012)
Severe Chronic Pancreatitis due to Recurrent Acute Injury: Non-Invasive Chronic Pancreatitis Model of Rat
Surendra Sharma
Pancreas (2016)
An internal sensor detects dietary amino acids and promotes food consumption in Drosophila
Zhe Yang
Nature (2017)
Enyong Dai et al.
Nature communications, 11(1), 6339-6339 (2020-12-15)
Ferroptosis is a more recently recognized form of cell death that relies on iron-mediated oxidative damage. Here, we evaluate the impact of high-iron diets or depletion of Gpx4, an antioxidant enzyme reported as an important ferroptosis suppressor, in the pancreas

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