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Merck
CN

909564

Sigma-Aldrich

4-Azido-L-phenylalanine

≥98%

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别名:
3-(p-Azidophenyl)-L-alanine hydrochloride, 4-Azidophenylalanine hydrochloride, 4-N3-L-Phenylalanine, p-Azido-L-phenylalanine hydrochloride, p-Azido-Phe*HCl, p-Azidophenylalanine hydrochloride, H-4-Azido-Phe*HCl, H-L-4-Azido-Phe-OH, H-L-Phe(4-N3)-OH, H-Phe(4-N3)*HCl, Phe(pN3)*HCl
经验公式(希尔记法):
C9H10N4O2
CAS号:
分子量:
206.20
MDL编号:
UNSPSC代码:
12352005

检测方案

≥98%

形式

powder

反应适用性

reaction type: click chemistry
reaction type: solution phase peptide synthesis

存货情况

available only in USA

储存温度

−20°C

InChI

1S/C9H10N4O2/c10-8(9(14)15)5-6-1-3-7(4-2-6)12-13-11/h1-4,8H,5,10H2,(H,14,15)/t8-/m0/s1

InChI key

NEMHIKRLROONTL-QMMMGPOBSA-N

应用

The in-vivo incorporation of clickable unnatural amino acids such as 4-Azido-L-phenylalanine with unique reactivity at a defined postition is used for functionalization of proteins. The azide functionalities in the protein can then be modified with almost any alkyne bearing molecule by Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). Copper-free alternatives with strained internal alkynes are also available (SPAAC). Some examples enabled with this technique are protein PEGylation, masking with sugars, and the attachment to antibodies.

相关产品

象形图

Flame

警示用语:

Danger

危险声明

危险分类

Self-react. C

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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