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线性分子式:
ClCO(CH2)8COCl
化学文摘社编号:
分子量:
239.14
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-843-4
Beilstein/REAXYS Number:
1365665
MDL number:
产品名称
癸二酰氯, purum, ≥95.0% (GC)
InChI key
WMPOZLHMGVKUEJ-UHFFFAOYSA-N
InChI
1S/C10H16Cl2O2/c11-9(13)7-5-3-1-2-4-6-8-10(12)14/h1-8H2
SMILES string
ClC(=O)CCCCCCCCC(Cl)=O
grade
purum
assay
≥95.0% (GC)
form
liquid
refractive index
n20/D 1.468 (lit.)
n20/D 1.468
bp
168 °C/12 mmHg (lit.)
mp
−5-−3 °C (lit.)
density
1.119 g/mL at 20 °C
1.121 g/mL at 25 °C (lit.)
Quality Level
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Application
Sebacoyl chloride may be used along with hexamethylenediamine, during Schotten -Baumann reactions, to produce a polyamide (eg.Nylon 6,10).
General description
Sebacoyl chloride is a light yellow, pungent odored di-acryl chloride. It is soluble in hydrocarbons and ethers.It hydrolyzes in water, releasing hydrogen chloride.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
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Zhe Gong et al.
ACS biomaterials science & engineering, 6(11), 6331-6343 (2021-01-16)
Despite decades of research, spinal cord injury (SCI) still causes irreparable damage to the human body. Key challenges that hinder the regeneration and extension of neurons following SCI must be overcome, including the overexpressed glial scar formation and strong inflammatory
P L Madan et al.
Pharmaceutical research, 6(8), 714-718 (1989-08-01)
The effect of selected variables on the release characteristics of theophylline microcapsules prepared with 1,6-hexamethylene diamine and sebacoyl chloride via interfacial polycondensation has been investigated. The nature of the microcapsules and the release characteristics of theophylline from the microcapsules were
Marianna Sikorska et al.
BioFactors (Oxford, England), 18(1-4), 173-183 (2003-12-30)
We have derivatised alpha-tocopherol (vitamin E) to a water-soluble polyoxyethanyl-alpha - tocopheryl sebacate (PTS) and discovered that it formed a non-covalent complex with CoQ10 at a molar ratio of 2:1 (PTS-CoQ10). This complex was water-soluble and remained stable for extended
Zhenhua Xu et al.
International journal of pharmaceutics, 426(1-2), 182-192 (2012-01-24)
In this study we describe a novel polymer, mPPS-FA, synthesized as a potential gene transfer vector. To complete mPPS-FA, folic acid was conjugated to a backbone (named mPPS) consisting of a copolymer of methyl PEG-2000, PEI-600, and sebacoyl chloride. (1)H
D Poncelet et al.
Journal of microencapsulation, 11(1), 31-40 (1994-01-01)
A microencapsulation technique is proposed involving the formation of a polyethyleneimine (PEI) membrane crosslinked by an acid dichloride. The membranes were formed at pH 8 in a non-polar solvent, conditions which are better suited for the encapsulation of biocatalysts or
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