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Merck
CN

81172

Sigma-Aldrich

聚(乙二醇)

tested according to Ph. Eur., 400

别名:

Macrogol 400, PEG

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About This Item

线性分子式:
H(OCH2CH2)nOH
CAS号:
MDL编号:
UNSPSC代码:
12352104
PubChem化学物质编号:
NACRES:
NA.21

Agency

tested according to Ph. Eur.

质量水平

表单

liquid

分子量

380-420

应用

pharmaceutical (small molecule)

SMILES字符串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般描述

聚乙二醇(PEG)是一种具有重复乙二醇单元[-(CH2CH2O)n]的聚醚化合物

应用

聚乙二醇已被用作液体介质,通过将其与发烟二氧化硅直接混合来制备剪切增稠液(STF)。

生化/生理作用

聚乙二醇(PEG)是一种合成聚合物,用作食品、化妆品和药品的添加剂。它还参与生物传感、成像和组织工程等生物医学应用。PEG 被用作生物偶联和纳米医学的金标准,从而增加血液循环时间并提高药物疗效。PEG 偶联药物已获得美国食品药品监督管理局(FDA)的批准。它们被认为对人类使用是安全的。PEG 减少肝脏摄取并排斥蛋白质吸附,这使其在纳米涂层中很好用。

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The rheology of shear thickening fluids with various ceramic particle additives
Gurgen S, et al.
Materials & Design, 104, 312-319 (2016)
The ballistic performance of aramid based fabrics impregnated with multi-phase shear thickening fluids
Gurgen S and Kucshan MC
Polymer Testing, 64, 296-306 (2017)
The stab resistance of fabrics impregnated with shear thickening fluids including various particle size of additives
Gurgen S and Kucshan MC
Composites Part A: Applied Science and Manufacturing, 94, 50-60 (2017)
Anisha A D'souza et al.
Expert opinion on drug delivery, 13(9), 1257-1275 (2016-04-28)
Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This USFDA-approved polymer is popular due to its tunable properties and well-established safety profile: prime requisites considered during the selection of any excipient in formulation development. The unique
Janina-Miriam Noy et al.
Biomacromolecules, 21(6), 2320-2333 (2020-04-29)
Phosphorylcholine is known to repel the absorption of proteins onto surfaces, which can prevent the formation of a protein corona on the surface of nanoparticles. This can influence the fate of nanoparticles used for drug delivery. This material could therefore

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