Agency
tested according to Ph. Eur.
质量水平
形式
liquid
分子量
380-420
应用
pharmaceutical (small molecule)
SMILES字符串
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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一般描述
聚乙二醇（PEG）是一种具有重复乙二醇单元[-（CH2CH2O)n]的聚醚化合物。
应用
聚乙二醇已被用作液体介质，通过将其与发烟二氧化硅直接混合来制备剪切增稠液（STF）。
生化/生理作用
聚乙二醇（PEG）是一种合成聚合物，用作食品、化妆品和药品的添加剂。它还参与生物传感、成像和组织工程等生物医学应用。PEG 被用作生物偶联和纳米医学的金标准，从而增加血液循环时间并提高药物疗效。PEG 偶联药物已获得美国食品药品监督管理局（FDA）的批准。它们被认为对人类使用是安全的。PEG 减少肝脏摄取并排斥蛋白质吸附，这使其在纳米涂层中很好用。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
The stab resistance of fabrics impregnated with shear thickening fluids including various particle size of additives
Gurgen S and Kucshan MC
Composites Part A: Applied Science and Manufacturing, 94, 50-60 (2017)
The rheology of shear thickening fluids with various ceramic particle additives
Gurgen S, et al.
Materials & Design, 104, 312-319 (2016)
The ballistic performance of aramid based fabrics impregnated with multi-phase shear thickening fluids
Gurgen S and Kucshan MC
Polymer Testing, 64, 296-306 (2017)
Thai Thanh Hoang Thi et al.
Polymers, 12(2) (2020-02-07)
Poly(ethylene glycol) (PEG) is widely used as a gold standard in bioconjugation and nanomedicine to prolong blood circulation time and improve drug efficacy. The conjugation of PEG to proteins, peptides, oligonucleotides (DNA, small interfering RNA (siRNA), microRNA (miRNA)) and nanoparticles
Anisha A D'souza et al.
Expert opinion on drug delivery, 13(9), 1257-1275 (2016-04-28)
Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This USFDA-approved polymer is popular due to its tunable properties and well-established safety profile: prime requisites considered during the selection of any excipient in formulation development. The unique
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