所有图片(1)
别名:
Naproxen Impurity E (PhEur), (2S)-2-(6-Methoxy-2-naphthyl)propionic acid methyl ester, Methyl (αS)-6-methoxy-α-methyl-2-naphthaleneacetate, Methyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
经验公式（希尔记法）:
C15H16O3
CAS号:
分子量:
244.29
Beilstein:
4352971
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.24
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质量水平
API类
naproxen
检测方案
≥98.0% (HPLC)
旋光性
[α]/D 72.0 to 84.0°, c = 0.1 in chloroform
保质期
limited shelf life, expiry date on the label
杂质
≤0.5% water
mp
87 °C
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-8°C
SMILES字符串
C[C@H](C(OC)=O)C1=CC2=CC=C(OC)C=C2C=C1
InChI
1S/C15H16O3/c1-10(15(16)18-3)11-4-5-13-9-14(17-2)7-6-12(13)8-11/h4-10H,1-3H3/t10-/m0/s1
InChI key
ZFYFBPCRUQZGJE-JTQLQIEISA-N
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一般描述
(S)-Naproxen methyl ester is an ester of the non-steroidal, anti-inflammatory drug, (S)-naproxen
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Enantioselective hydrolysis of racemic naproxen methyl ester by two-step acetone-treated Candida rugosa lipase.
Lee GE, et al.
Process Biochemistry (Oxford, United Kingdom), 37(3), 293-298 (2001)
Bulletin of the Chemical Society of Japan, 77(1-4) (2004)
Sammy Ferri-Borgogno et al.
Cancers, 12(9) (2020-09-25)
Background & Aims: ARID1A is postulated to be a tumor suppressor gene owing to loss-of-function mutations in human pancreatic ductal adenocarcinomas (PDAC). However, its role in pancreatic pathogenesis is not clear despite recent studies using genetically engineered mouse (GEM) models.
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