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Merck
CN

80821

Supelco

(2S)-2-(5-Iodo-6-methoxynaphthalen-2-yl)propanoic acid

pharmaceutical impurity standard

别名:

Naproxen Impurity D (PhEur), (αS)-5-Iodo-6-methoxy-α-methyl-2-naphthaleneacetic acid, (2S)-2-(5-Iodo-6-methoxy-2-naphthyl)propionic acid, (S)-5-Iodo naproxen, Naproxen EP Impurity D

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About This Item

经验公式(希尔记法):
C14H13IO3
分子量:
356.16
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.24

质量水平

API类

naproxen

方案

≥98.0% (HPLC)

旋光性

[α]/D 41±4°, c = 1 in chloroform

保质期

limited shelf life, expiry date on the label

杂质

≤0.5% water

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

C[C@H](C(O)=O)C1=CC2=CC=C(OC)C(I)=C2C=C1

InChI

1S/C14H13IO3/c1-8(14(16)17)9-3-5-11-10(7-9)4-6-12(18-2)13(11)15/h3-8H,1-2H3,(H,16,17)/t8-/m0/s1

InChI key

MNTGUQDQTXNYMT-QMMMGPOBSA-N

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说明
价格

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ina N Eckert et al.
Frontiers in immunology, 11, 616531-616531 (2021-02-16)
Myeloid-derived suppressor cells (MDSCs) represent a major population controlling T cell immune responses. However, little is known about their molecular requirements for homing and T cell interaction to mediate suppression. Here, we investigated the functional role of the homing and
Alex Kiepas et al.
Journal of cell science, 133(4) (2020-01-29)
Fluorescence illumination can cause phototoxicity that negatively affects living samples. This study demonstrates that much of the phototoxicity and photobleaching experienced with live-cell fluorescence imaging occurs as a result of 'illumination overhead' (IO). This occurs when a sample is illuminated
Cyril Andrieu et al.
Development (Cambridge, England), 147(7) (2020-04-14)
Matrix metalloproteinases have a broad spectrum of substrates ranging from extracellular matrix components and adhesion molecules to chemokines and growth factors. Despite being mostly secreted, MMPs have been detected in the cytosol, the mitochondria or the nucleus. Although most of
María Rodríguez-López et al.
Cell reports, 30(10), 3240-3249 (2020-03-12)
Target of Rapamycin Complex 1 (TORC1) signaling promotes growth and aging. Inhibition of TORC1 leads to reduced protein translation, which promotes longevity. TORC1-dependent post-transcriptional regulation of protein translation has been well studied, while analogous transcriptional regulation is less understood. Here

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