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Merck
CN

76078

SAFC

L-蛋氨酸亚砜酰亚胺

制药生产

别名:

L-S-(3-氨基-3-羧丙基)-S-甲基砜亚胺

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About This Item

线性分子式:
CH3S(O)(=NH)CH2CH2CH(NH2)CO2H
CAS号:
分子量:
180.23
Beilstein:
6175446
MDL编号:
UNSPSC代码:
12352200

生物来源

synthetic

质量水平

检测方案

≥96% (rel., HPLC)

形式

solid

旋光性

[α]20/D +10.8 to +14.0°, c = 1 in H2O

浓度

95-102 % (w/w) (HPLC)

杂质

≤0.1% each single unknown impurity (rel.)
≤0.5% sulfated ash
≤0.5% water (Karl Fischer)
≤1% methionine sulfone (rel.)
≤1% methionine sulfoxide (rel.)
≤10 mg/kg azide
≤2% methionine (rel.)
≤5000 ppm ethanol (GC-HS)

mp

>210 °C (dec.) (lit.)

适用性

complies for H-NMR
complies for identity (HPLC)

SMILES字符串

CS(=N)(=O)CC[C@H](N)C(O)=O

InChI

1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1

InChI key

SXTAYKAGBXMACB-DPVSGNNYSA-N

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象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Ji Wang et al.
PloS one, 6(3), e18233-e18233 (2011-04-13)
The membrane-proximal external region (MPER) of the HIV-1 gp41 consists of epitopes for the broadly cross-neutralizing monoclonal antibodies 2F5 and 4E10. However, antigens containing the linear sequence of these epitopes are unable to elicit potent and broad neutralizing antibody responses
Hsiu-Ni Kung et al.
PLoS genetics, 7(8), e1002229-e1002229 (2011-08-20)
Although significant variations in the metabolic profiles exist among different cells, little is understood in terms of genetic regulations of such cell type-specific metabolic phenotypes and nutrient requirements. While many cancer cells depend on exogenous glutamine for survival to justify
Evan T Brower et al.
Biochemistry, 48(4), 779-785 (2009-01-28)
The initial events of HIV-1 cell infection involve the sequential binding of the viral envelope glycoprotein gp120 to the cellular CD4 receptor and the coreceptor, usually CCR5 or CXCR4. Binding to the coreceptor triggers the chain of events that culminates
Marilynn A Larson et al.
The Biochemical journal, 462(2), 329-335 (2014-06-12)
Human BChE (butyrylcholinesterase) protects against the toxicity of organophosphorus nerve agents and pesticides. BChE purified from human plasma is limited and pathogen carry-over is a concern. Unlike the native BChE tetrameric complex with a residence time of days, rBChE (recombinant
Aneesh Vijayan et al.
PloS one, 10(7), e0133595-e0133595 (2015-07-25)
In the HIV vaccine field, there is a need to produce highly immunogenic forms of the Env protein with the capacity to trigger broad B and T-cell responses. Here, we report the generation and characterization of a chimeric HIV-1 gp120

实验方案

LC/MS Analysis of L-Methionine Sulfoximine and Sulfone on Ascentis® Express OH5

Separation of L-Methionine sulfone; L-Methionine sulfoximine; L-Methionine sulfoxide

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