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Agency
ISO 29981:2010
质量水平
无菌性
sterile (Filtered and Aseptic Handled)
sterile
形式
liquid
保质期
limited shelf life, expiry date on the label
应用
environmental
food and beverages
microbiology
储存温度
2-8°C
适用性
Lactobacillus spp.
Lactococcus spp.
Leuconostoc spp.
Streptococcus spp.
SMILES字符串
[Li+].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]2CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]2O
InChI
1S/C26H44O9.Li/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);/q;+1/p-1/b16-13+;/t17-,18-,19-,20-,21-,24+,25-,26-;/m0./s1
InChI key
XFIKMPRBSORKQP-JATHGWPISA-M
一般描述
Lithium mupirocin is isolated from Pseudomonas fluorescens. At lower concentrations, it has bacteriostatic characteristics, while at higher concentrations it is bacteriocidal. Mupirocin is active against gram-positive bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA), Lactobacilli, Lactococci, Streptococci and Leuconostocs. Mupirocin has been used to study mupirocin resistance in Mycoplasma bacteria. Mupirocin inhibits the isoleucyl-tRNA synthetase, which finally results in inhibition of protein and RNA synthesis. Mupirocin lithium salt is freely soluble in water.
应用
Lithium mupirocin supplement is used for selective enumeration of Bifidobacteria from fermented milk products along with the TOS-propionate agar according to ISO 29981:2010 and IDF 220:2010
组分
Composition:
(5ml, sufficient for 100 ml medium)
Mupirocin 5 mg
sterile distilled water 5.0 ml
(5ml, sufficient for 100 ml medium)
Mupirocin 5 mg
sterile distilled water 5.0 ml
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
J Gilbart et al.
Antimicrobial agents and chemotherapy, 37(1), 32-38 (1993-01-01)
Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four
Variation, viability and validity of bifidobacteria in fermented milk products.
Raeisi, Shahram Naghizadeh, et al.
Food Control, 34, 691-697 (2013)
Emergence of methicillin-resistant Staphylococcus aureus ST239 with high-level mupirocin and inducible clindamycin resistance in a tertiary care center in Chennai, South India.
Nagarajan Abimanyu et al.
Journal of clinical microbiology, 50(10), 3412-3413 (2012-08-03)
Tomás García-Lozano et al.
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 25(4), 252-255 (2013-01-11)
Our objective was to determine the prevalence of methicillin-resistant Staphylococcus aureus in workers who had direct contact with oncologic patients infected with MRSA and admitted to the intensive care unit of the Valencian Institute of Oncology. A study of prevalence
Yi-Yuan Chiu et al.
BMC genomics, 13 Suppl 7, S21-S21 (2013-01-11)
To discover a compound inhibiting multiple proteins (i.e. polypharmacological targets) is a new paradigm for the complex diseases (e.g. cancers and diabetes). In general, the polypharmacological proteins often share similar local binding environments and motifs. As the exponential growth of
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