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Merck
CN

69732

Millipore

Lithium mupirocin Supplement

suitable for microbiology,

Selectively inhibits the growth of lactic acid bacteria

别名:

Lithium mupirocin solution, Li-MUP, MUP supplement

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About This Item

经验公式(希尔记法):
C26H43LiO9
CAS号:
分子量:
506.56
MDL编号:
UNSPSC代码:
41171614
PubChem化学物质编号:
NACRES:
NA.85

Agency

ISO 29981:2010

质量水平

无菌性

sterile (Filtered and Aseptic Handled)
sterile

表单

liquid

保质期

limited shelf life, expiry date on the label

应用

environmental
food and beverages

microbiology

储存温度

2-8°C

适用性

Lactobacillus spp.
Lactococcus spp.
Leuconostoc spp.
Streptococcus spp.

SMILES字符串

[Li+].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]2CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]2O

InChI

1S/C26H44O9.Li/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);/q;+1/p-1/b16-13+;/t17-,18-,19-,20-,21-,24+,25-,26-;/m0./s1

InChI key

XFIKMPRBSORKQP-JATHGWPISA-M

一般描述

Lithium mupirocin is isolated from Pseudomonas fluorescens. At lower concentrations, it has bacteriostatic characteristics, while at higher concentrations it is bacteriocidal. Mupirocin is active against gram-positive bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA), Lactobacilli, Lactococci, Streptococci and Leuconostocs. Mupirocin has been used to study mupirocin resistance in Mycoplasma bacteria. Mupirocin inhibits the isoleucyl-tRNA synthetase, which finally results in inhibition of protein and RNA synthesis. Mupirocin lithium salt is freely soluble in water.

应用

Lithium mupirocin supplement is used for selective enumeration of Bifidobacteria from fermented milk products along with the TOS-propionate agar according to ISO 29981:2010 and IDF 220:2010

组分

Composition:
(5ml, sufficient for 100 ml medium)
Mupirocin 5 mg
sterile distilled water 5.0 ml

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Variation, viability and validity of bifidobacteria in fermented milk products.
Raeisi, Shahram Naghizadeh, et al.
Food Control, 34, 691-697 (2013)
J Gilbart et al.
Antimicrobial agents and chemotherapy, 37(1), 32-38 (1993-01-01)
Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four
Tomás García-Lozano et al.
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 25(4), 252-255 (2013-01-11)
Our objective was to determine the prevalence of methicillin-resistant Staphylococcus aureus in workers who had direct contact with oncologic patients infected with MRSA and admitted to the intensive care unit of the Valencian Institute of Oncology. A study of prevalence
Yi-Yuan Chiu et al.
BMC genomics, 13 Suppl 7, S21-S21 (2013-01-11)
To discover a compound inhibiting multiple proteins (i.e. polypharmacological targets) is a new paradigm for the complex diseases (e.g. cancers and diabetes). In general, the polypharmacological proteins often share similar local binding environments and motifs. As the exponential growth of
Kristin A Seiberling et al.
International forum of allergy & rhinology, 3(2), 94-98 (2012-11-30)
Antibiotic irrigations are occasionally used during endoscopic sinus surgery when gross mucosal infection is present. These irrigations are thought to flush out pathogenic bacteria and decrease the bacterial load within the mucosal surfaces. This treatment, however, has not been studied

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