68459
乙琥胺
analytical standard
别名:
2-乙基-2-甲基琥珀酰亚胺
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经验公式（希尔记法）:
C7H11NO2
化学文摘社编号:
分子量:
141.17
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
201-048-7
MDL number:
InChI key
HAPOVYFOVVWLRS-UHFFFAOYSA-N
InChI
1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
SMILES string
O=C1NC(CC1(C)CC)=O
grade
analytical standard
assay
≥98.0% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
Gene Information
human ... CACNA1G(8913), CACNA1H(8912), CACNA1I(8911)
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
S J Wallace
Epilepsy research, 29(2), 147-154 (1998-02-26)
Based on small numbers of patients, it is possible to make the following suggestions rather than categorical statements. For myoclonic seizures and epilepsies which are not otherwise specified, valproate seems of proven efficacy. Ethosuximide may be a useful adjunct. The
Sloka S Iyengar et al.
Experimental neurology, 264, 135-149 (2014-12-06)
Adult neurogenesis, the generation of new neurons in the adult brain, occurs in the hippocampal dentate gyrus (DG) and the olfactory bulb (OB) of all mammals, but the functions of these new neurons are not entirely clear. Originally, adult-born neurons
[Ethosuximide].
M Ichiba et al.
Nihon rinsho. Japanese journal of clinical medicine, 53 Su Pt 1, 915-917 (1995-02-01)
J S Millership et al.
European journal of drug metabolism and pharmacokinetics, 18(4), 349-353 (1993-10-01)
The metabolism of the antiepileptic drug ethosuximide (3-ethyl-3-methylpyrollidine-2,5-dione) (I) in animals and humans is reviewed. Chiral aspects of the metabolism of ethosuximide are discussed. Clarification of the precise nature of the hydroxymetabolites of ethosuximide is presented.
E B Posner et al.
The Cochrane database of systematic reviews, (3)(3), CD003032-CD003032 (2003-08-15)
Absence seizures are brief epileptic seizures which present in childhood and adolescence. They are characterised by sudden loss of awareness and an electroencephalogram (EEG) typically shows generalised spike wave discharges at three cycles per second. Ethosuximide, valproate and lamotrigine are
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