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Merck
CN

CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

别名:
CACNA1HB, Cav3.2, ECA6, EIG6
物种:
UniProtKB ID:
基因ID:
  • Human(8912) Summary: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
  • Mouse(58226) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • Rat(114862) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • dog(403533) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic cat(101090071) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic guinea pig(100720102) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • naked mole-rat(101712631) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • chicken(416526) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • cow(282412) calcium channel, voltage-dependent, T type, alpha 1H subunit

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Small Molecule - Allosteric Modulator

货号
说明
物种
加巴喷丁, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
加巴喷丁标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
加巴喷丁, United States Pharmacopeia (USP) Reference Standard,
物种
human
普瑞巴林, European Pharmacopoeia (EP) Reference Standard,
物种
human
加巴喷丁, European Pharmacopoeia (EP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
抗-钙通道CaV3.2(α1H) 兔抗, affinity isolated antibody, lyophilized powder,
物种反应性
rat
应用
western blot
Anti-CACNA1H antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
Anti-CACNA1H antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-Cav3.2 Antibody, Chemicon®, from rabbit,
物种反应性
rat
应用
western blot

Small Molecule - Blocker

货号
说明
物种
乙琥胺, ,
物种
human
乙琥胺, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
乙琥胺, United States Pharmacopeia (USP) Reference Standard,
物种
human
三甲双酮, European Pharmacopoeia (EP) Reference Standard,
物种
human
乙琥胺, European Pharmacopoeia (EP) Reference Standard,
物种
human