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文件

1287303

USP

加巴喷丁

Name: 加巴喷丁
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

1-（氨甲基）-环己烷乙酸, 加巴喷丁

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About This Item

经验公式（希尔记法）:

C₉H₁₇NO₂

CAS号:

60142-96-3

分子量:

171.24

Beilstein:

2359739

MDL编号:

MFCD00865286

UNSPSC代码:

41116107

PubChem化学物质编号:

329749919

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

gabapentin

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

NCC1(CC(O)=O)CCCCC1

InChI

1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)

InChI key

UGJMXCAKCUNAIE-UHFFFAOYSA-N

基因信息

human ... CACNA1A(773) , CACNA1B(774) , CACNA1C(775) , CACNA1D(776) , CACNA1E(777) , CACNA1F(778) , CACNA1G(8913) , CACNA1H(8912) , CACNA1I(8911) , CACNA1S(779) , CACNA2D1(781) , CACNA2D2(9254) , CACNA2D3(55799) , CACNA2D4(93589) , CACNB1(782) , CACNB2(783) , CACNB3(784) , CACNB4(785) , CACNG1(786) , CACNG2(10369) , CACNG3(10368) , CACNG4(27092) , CACNG5(27091) , CACNG6(59285) , CACNG7(59284) , CACNG8(59283)

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应用

Gabapentin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

Gabapentin Capsules
Gabapentin Tablets
Gabapentin Compounded Cream
Gabapentin Compounded Oral Suspension

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

Sales restrictions may apply.

1287325

1287347

1287358

1287369

Y0001281

加巴喷丁杂质A, European Pharmacopoeia (EP) Reference Standard

Y0001348

加巴喷丁杂质B, European Pharmacopoeia (EP) Reference Standard

PHR1322

PHR2013

PHR2011

PHR2012

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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ESTIMATION OF GABAPENTIN IN HUMAN PLASMA USING LC-MS/MS METHOD.

Das, Binaya.

Asian Journal of Pharmaceutical and Clinical Research, 6.3, 213-216 (2013)

The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel.

N S Gee et al.

The Journal of biological chemistry, 271(10), 5768-5776 (1996-03-08)

Gabapentin (1-(aminomethyl)cyclohexane acetic acid; Neurontin) is a novel anticonvulsant drug, with a mechanism of action apparently dissimilar to that of other antiepileptic agents. We report here the isolation and characterization of a [3H]gabapentin-binding protein from pig cerebral cortex membranes. The

Gabapentin therapy of hiccups.

Dennis F Thompson et al.

The Annals of pharmacotherapy, 47(6), 897-903 (2013-05-16)

To determine whether gabapentin is effective in the treatment of persistent or intractable hiccups. A search of MEDLINE (1966-March 2013) using the MeSH search terms gabapentin, hiccups, and hiccups/drug therapy was performed. Additional databases searched included Web of Science (1945-March

Gabapentin for pruritus in palliative care.

Sheeba Anand

The American journal of hospice & palliative care, 30(2), 192-196 (2012-05-05)

Itch/pruritus can be very distressing in palliative care population and often is difficult to treat. Conventional antihistamines lack efficacy. Cutaneous and central pathogenesis of itch is extremely complex and unclear, making its treatment challenging. Neuronal mechanisms have been identified in

Gabapentin for once-daily treatment of post-herpetic neuralgia: a review.

Benjamin Beal et al.

Clinical interventions in aging, 7, 249-255 (2012-08-07)

Post-herpetic neuralgia is a neuropathic pain syndrome resulting from an insult to the peripheral and central nervous systems caused by the varicella zoster virus. Spontaneous pain may result in the persistent sensation of burning, tingling, or aching and may be

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