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Merck
CN

51239

Millipore

土霉素盐酸盐

suitable for microbiology

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别名:
Oxytetracycline, OGYE Selective Supplement
经验公式(希尔记法):
C22H24N2O9
CAS号:
分子量:
460.43
EC 号:
MDL编号:
UNSPSC代码:
41171614
PubChem化学物质编号:
NACRES:
NA.85

无菌性

sterile

质量水平

形式

powder

保质期

limited shelf life, expiry date on the label

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

应用

environmental
food and beverages
pharmaceutical

microbiology

作用机制

protein synthesis | interferes

适用性

molds
yeasts

SMILES字符串

CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

InChI

1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1

InChI key

IWVCMVBTMGNXQD-PXOLEDIWSA-N

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一般描述

Chemical structure: tetracycline

应用

Oxytetracycline is used as an antibacterial selective agent in microbiology studies . It is a broad spectrum antibiotic that is active against a wide variety of bacteria. When added to OGY-Agar (Cat. No. 75310) Oxytetracycline suppresses the growth of accompanying bacterial flora during culturing yeasts and molds.

生化/生理作用

Oxytetracycline is a protein synthesis inhibitor .

特点和优势

Added to OGY-Agar (Cat. No. 75310) or OGYE ChromoSelect Agar (Cat. No. 66481) Oxytetracycline suppresses the growth of accompanying bacterial flora during culturing yeasts and moulds.

组分

(per vial sufficient for 500 ml medium)
Oxytetracycline 50.0 mg

相关产品

象形图

Health hazardEnvironment

警示用语:

Warning

危险声明

危险分类

Aquatic Chronic 2 - Repr. 2

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

分析证书(COA)

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E M MIKOLAJCIK et al.
Applied microbiology, 11, 418-422 (1963-09-01)
Induction of oxytetracycline resistance in a strain of Streptococcus lactis caused this organism to display reduced acid production, salt tolerance, pyruvate synthesis, growth at alkaline pH, and a loss in ability to produce ammonia from arginine. alpha-Ketoglutaric and oxaloacetic acids
Pavel Novy et al.
The Journal of antimicrobial chemotherapy, 66(6), 1298-1300 (2011-03-23)
In this study we examined the in vitro synergistic effect of baicalin, the flavone constituent of Scutellaria spp., in combinations with oxytetracycline and tetracycline on the growth of Staphylococcus aureus. The MICs were determined by the broth microdilution method and
P R Spooner
Parasitology, 101 Pt 3, 387-393 (1990-12-01)
Oxytetracycline (OTC) significantly inhibited cytochrome c oxidase activity in bovine lymphocytes infected with Theileria parva and in uninfected mitogen-stimulated lymphocytes. The inhibitory effect was detected in vitro within 24 h of treatment with drug concentrations as low as 1 micrograms/ml.
Miaomiao Liu et al.
Applied microbiology and biotechnology, 97(19), 8805-8812 (2012-11-29)
To investigate how the microbial community in activated sludge responded to high antibiotic levels, a bench-scale aerobic wastewater treatment system was used to treat oxytetracycline (OTC) mother liquor (OTC-ML). Removal efficiency of chemical oxygen demand decreased from 64.9 to 51.0 %
Getu Kahsay et al.
Journal of pharmaceutical and biomedical analysis, 75, 199-206 (2013-01-02)
A simple, robust and fast high-performance liquid chromatographic method is described for the analysis of oxytetracycline and its related impurities. The principal peak and impurities are all baseline separated in 20 min using an Inertsil C₈ (150 mm × 4.6

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