51239
土霉素盐酸盐
suitable for microbiology
别名:
Oxytetracycline, OGYE Selective Supplement
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关于此项目
经验公式（希尔记法）:
C22H24N2O9
化学文摘社编号:
分子量:
460.43
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
41171614
EC Number:
201-212-8
MDL number:
InChI
1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1
InChI key
IWVCMVBTMGNXQD-PXOLEDIWSA-N
SMILES string
CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O
sterility
sterile
form
powder
shelf life
limited shelf life, expiry date on the label
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
application(s)
environmental
food and beverages
pharmaceutical, microbiology
mode of action
protein synthesis | interferes
suitability
molds, yeasts
Quality Level
General description
Chemical structure: tetracycline
Application
Oxytetracycline is used as an antibacterial selective agent in microbiology studies . It is a broad spectrum antibiotic that is active against a wide variety of bacteria. When added to OGY-Agar (Cat. No. 75310) Oxytetracycline suppresses the growth of accompanying bacterial flora during culturing yeasts and molds.
Biochem/physiol Actions
Oxytetracycline is a protein synthesis inhibitor .
Features and Benefits
Added to OGY-Agar (Cat. No. 75310) or OGYE ChromoSelect Agar (Cat. No. 66481) Oxytetracycline suppresses the growth of accompanying bacterial flora during culturing yeasts and moulds.
Other Notes
(per vial sufficient for 500 ml medium)
Oxytetracycline 50.0 mg
Oxytetracycline 50.0 mg
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
E M MIKOLAJCIK et al.
Applied microbiology, 11, 418-422 (1963-09-01)
Induction of oxytetracycline resistance in a strain of Streptococcus lactis caused this organism to display reduced acid production, salt tolerance, pyruvate synthesis, growth at alkaline pH, and a loss in ability to produce ammonia from arginine. alpha-Ketoglutaric and oxaloacetic acids
Pavel Novy et al.
The Journal of antimicrobial chemotherapy, 66(6), 1298-1300 (2011-03-23)
In this study we examined the in vitro synergistic effect of baicalin, the flavone constituent of Scutellaria spp., in combinations with oxytetracycline and tetracycline on the growth of Staphylococcus aureus. The MICs were determined by the broth microdilution method and
P R Spooner
Parasitology, 101 Pt 3, 387-393 (1990-12-01)
Oxytetracycline (OTC) significantly inhibited cytochrome c oxidase activity in bovine lymphocytes infected with Theileria parva and in uninfected mitogen-stimulated lymphocytes. The inhibitory effect was detected in vitro within 24 h of treatment with drug concentrations as low as 1 micrograms/ml.
A L Stanton et al.
Journal of dairy science, 95(9), 4950-4960 (2012-08-25)
Bovine respiratory disease complex (BRD) is a common disease in weaned dairy calves that incurs economic and welfare costs. This study was an extension of a randomized clinical trial in which a single injection of tulathromycin (TUL) or oxytetracycline (TET)
Guang-Feng Yang et al.
Bioresource technology, 129, 65-71 (2012-12-13)
The short- and long-term effects of oxytetracycline (OTC) on the anaerobic ammonium oxidation (Anammox) process were evaluated. The OTC inhibition of Anammox was substrate-, and especially nitrite-, dependent. The IC50 of OTC in the batch tests on an Anammox mixed
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