跳转至内容
Merck
CN
所有图片(3)

文件

48912-U

Sigma-Aldrich

ProClin™ 300

pkg of 50 mL, ProClin™ preservative for use in IVD manufacturing, CMIT/MIT 3 %

登录查看公司和协议定价
所有图片(3)
别名:
3% 5-氯-2-甲基-4-异噻唑啉-3-酮和2-甲基-4-异噻唑啉-3-酮溶液
UNSPSC代码:
12352201
NACRES:
NA.21

质量水平

300

形式

liquid

保质期

3 yr

包含

Alkyl Carboxylate

组成

CMIT/MIT, 3%

包装

pkg of 50 mL

参数

<45 °C operating temperature

颜色

colorless to light yellow

基质

Modified glycol

operating pH range

2.5-8.5

pH值（酸碱度）

4.1 (100 g/L)

bp

189 °C

mp

-40 °C

溶解性

water: soluble

密度

1.03 g/cm3

正在寻找类似产品? 访问 产品对比指南

相关类别

一般描述

ProClin™ 防腐剂是一种的水溶性杀菌制剂，通常用于延长试剂的保质期。ProClin™ 300 由 3% 的 5-氯-2-甲基-4-异噻唑啉-3-酮(CMIT) 和 2-甲基-4-异噻唑啉-3-酮 (MIT) 组成，溶于含有烷基羧酸盐的无盐专有乙二醇稳定剂中。推荐工作 pH 范围为 2.5 - 8.5。

应用

ProClin™ 300 适用于制备不同的缓冲液，如 ELISA 缓冲液、样品和底物稀释缓冲液，用于单分子阵列（Simoa 分析）和免疫酶分析。此外，ProClin™ 可用于制备储存缓冲液，以储存与冠状病毒核衣壳蛋白偶联的珠子，并用于血清学多重检测。
仅限生物诊断检测和体外诊断检测使用
ProClin™ biocides preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin™ toxicity prevent microorganisms from developing high levels of resistance, making ProClin™ highly efficient even over extended storage periods of your IVD components.

生化/生理作用

ProClin™ 产品包含例如 CMIT 和 MIT等活性物质，它们可在四个不同的检查点抑制三羧酸循环，分别为丙酮酸脱氢酶、α-酮戊二酸脱氢酶、琥珀酸脱氢酶和NADH脱氢酶。三羧酸循环的抑制可实现对细菌、真菌和酵母的有效广谱杀灭活性。

法律信息

ProClin is a trademark of LANXESS Corp.

免责声明

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

警示用语：

Danger

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the concentration of active ingredients in ProClin 300?

    ProClin 300 contains a total of 3% active ingredient.

  4. What is the matrix of the ProClin 300?

    ProClin 300 is a viscous solution containing 93-95 % Modified glycol and 2-3 % Alkyl carboxylate.

  5. When would I choose to use ProClin 300?

    ProClin 300 is best used with production runs of standards, controls, and large volume buffers and solutions.  The product is quite viscous and difficult to work with when trying to measure small volumes.

  6. What are the active ingredients in ProClin 300?

    ProClin 300 contains two active ingredients: 5-Chloro-2-methyl-4-isothiazolin-3-one (CMIT, CAS RN 26172-55-4) and 2-Methyl-4-isothiazolin-3-one (MIT, CAS RN 2682-20-4).  

  7. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  8. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  9. What is the density of ProClin 300?

    The density of ProClin 300 is reported as 8.59 pounds per gallon. The specific gravity at 22°C is reported as 1.03 g/mL.

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Molecular-biological problems of drug design and mechanism of drug action
GI Khvatova and AV Semeikin
Journal of Pharmacy and Chemistry, 44(12), 651-653 (2011)
Annika Nelde et al.
Nature immunology, 22(1), 74-85 (2020-10-02)
T cell immunity is central for the control of viral infections. To characterize T cell immunity, but also for the development of vaccines, identification of exact viral T cell epitopes is fundamental. Here we identify and characterize multiple dominant and
Limor Cohen et al.
Journal of immunological methods, 452, 20-25 (2017-10-19)
Rats are used as animal models for many human diseases. Cytokines can serve as biomarkers indicative of these diseases or disease states. Techniques for measuring cytokine expression levels often do not provide the sensitivity needed to measure these biomarkers in
Single Molecule Arrays for ultra-sensitive detection of rat cytokines in serum
Cohen L, et al.
Journal of Immunological Methods, 452, 20-25 (2018)
SARS-CoV-2 T-cell epitopes define heterologous and COVID-19-induced T-cell recognition
Nelde A, et al.
Research (Washington, D.C.) (2020)
查看所有相关文献

实验方案

Determination of Silver in Water and Wastewater: Photometric Determination Using Phenanthroline Method and Eosin Y

The article describes the sample preparation and photometric determination of silver concentration in water samples using Spectroquant® photometers and test kits.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门