产品名称
聚山梨酯20, tested according to Ph. Eur.
SMILES string
O1C(C(C(C1)OCCO)OCCO)C(OCCO)COCCOC(=O)CCCCCCCCCCC
InChI
1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
InChI key
HMFKFHLTUCJZJO-UHFFFAOYSA-N
agency
USP/NF
tested according to Ph. Eur.
description
non-ionic
form
liquid
mol wt
~1228 g/mol
CMC
0.06
transition temp
cloud point 76 °C
HLB
16.7
application(s)
pharmaceutical (small molecule)
Quality Level
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Application
- 旨在降低游离脂肪酸颗粒形成风险的高纯度改良聚山梨酯20的评估。该研究评估了一种高纯度改良聚山梨酯20,旨在减少游离脂肪酸颗粒的形成。这种改良可能会提高生物制药制剂的稳定性和安全性(Doshi et al., 2021)。
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
527.0 °F - Pensky-Martens closed cup
flash_point_c
275 °C - Pensky-Martens closed cup
ppe
Eyeshields, Gloves
Gunasekaran Dhandapani et al.
mAbs, 11(3), 583-592 (2019-01-09)
We introduce a new concept and potentially general platform for antibody (Ab) purification that does not rely on chromatography or specific ligands (e.g., Protein A); rather, it makes use of detergent aggregates capable of efficiently capturing Ab while rejecting hydrophilic
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