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蒸汽压
0.58 mmHg ( 20 °C)
检测方案
≥97.0% (GC)
折射率
n20/D 1.385 (lit.)
bp
62 °C/9 mmHg (lit.)
mp
−82 °C (lit.)
密度
1.06 g/mL at 25 °C (lit.)
储存温度
2-8°C
SMILES字符串
CC(C)OP(F)(=O)OC(C)C
InChI
1S/C6H14FO3P/c1-5(2)9-11(7,8)10-6(3)4/h5-6H,1-4H3
InChI key
MUCZHBLJLSDCSD-UHFFFAOYSA-N
基因信息
human ... ACHE(43) , PTGS1(5742) , PTGS2(5743)
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生化/生理作用
丝氨酸蛋白酶（如胰蛋白酶和胰凝乳蛋白酶）和乙酰胆碱酯酶的强效抑制剂；还抑制组织蛋白酶 G、胆碱脂酶、凝血因子 Xa、白细胞弹性蛋白酶、胰弹性蛋白酶、组织激肽释放酶、血纤维蛋白熔酶、枯草杆菌蛋白酶以及凝血酶。乙酰胆碱酯酶的抑制作用使该化合物具有特别强的毒性。抑制由篦麻毒素和细菌毒素诱导的细胞凋亡。
分析说明
使用浓度通常为 0.10mM。苯甲基磺酰氟 (PMSF) 是一种更安全的丝氨酸蛋白酶替代抑制剂。
其他说明
Potent inhibitor of chymotrypsin and other enzymes (e.g. serine hydrolases); Inhibition of carboxypeptidase but not DAP I
警示用语：
Danger
危险分类
Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
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