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Merck
CN

37019

Supelco

阿托品

analytical standard

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别名:
(8-甲基-8-氮杂双环[3.2.1]辛-3-基) endo-(+/-)-α-(羟甲基)苯乙酸酯, 莨菪碱, 龙葵碱
经验公式(希尔记法):
C17H23NO3
CAS号:
分子量:
289.37
Beilstein:
91260
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

cleaning products
cosmetics
food and beverages
personal care

格式

neat

储存温度

−20°C

SMILES字符串

CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

InChI

1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?

InChI key

RKUNBYITZUJHSG-SPUOUPEWSA-N

基因信息

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一般描述

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.
Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.
For the analysis of the phytotoxins.

应用

Atropine may be used as a reference standard for the determination of atropine in:
  • Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
  • Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
  • Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
  • Plant materials by liquid-liquid extraction and EXtrelut® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Atropine may be used as a reference standard for the determination of atropine in:
  • Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
  • Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
  • Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
  • Plant materials by liquid-liquid extraction and EXtrelut® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

生化/生理作用

位于中枢和外周毒蕈碱型乙酰胆碱受体处的竞争性非选择性拮抗剂。

重悬

Dried down, ~100μg/mL after reconstitution with 1 mL of water

分析说明

purity : ≥96.0% (HPLC)

法律信息

Extrelut is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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Are tropane alkaloids present in organic foods? Detection of scopolamine and atropine in organic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
<BIG>Cirlini M, et al.</BIG>
Food Chemistry, 239, 141-147 (2018)
High-throughput screening for drugs of abuse and pharmaceutical drugs in hair by liquid-chromatography-high resolution mass spectrometry (LC-HRMS).
<BIG>Odoardi S, et al.</BIG>
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 133, 302-310 (2017)
Isolation of atropine and scopolamine from plant material using liquid-liquid extraction and EXtrelut columns
<BIG>Sramska P, et al.</BIG>
Journal of Chromatography. B, Biomedical Sciences and Applications, 1043, 202-208 (2017)
Enantiomeric determination and evaluation of the racemization process of atropine in Solanaceae seeds and contaminated samples by high performance liquid chromatography-tandem mass spectrometry.
<BIG>Marin-Saez J, et al.</BIG>
Journal of Chromatography A, 1474, 79-84 (2016)
Method validation for simultaneous determination of atropine, pralidoxime and 12 organophosphorus compounds in blood samples by means of high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).
<BIG>Marques GLM, et al</BIG>.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1097, 44-53 (2018)

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