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Merck
CN

09668

Sigma-Aldrich

N,N,N′,N′-四甲基脲-O-(N-琥珀酸亚胺基)六氟磷酸盐

≥99.0% (TLC/N)

别名:

N,N,N′,N′-四甲基-O-(N-琥珀酸亚胺基)脲六氟磷酸盐, HSTU

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About This Item

经验公式(希尔记法):
C9H16F6N3O3P
分子量:
359.21
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22

方案

≥99.0% (TLC/N)

表单

crystals

反应适用性

reaction type: Coupling Reactions

mp

218-221 °C (dec.)

溶解性

acetonitrile: 0.5 g/mL, slightly hazy, colorless

应用

peptide synthesis

储存温度

−20°C

SMILES字符串

F[P-](F)(F)(F)(F)F.CN(C)C(\ON1C(=O)CCC1=O)=[N+](\C)C

InChI

1S/C9H16N3O3.F6P/c1-10(2)9(11(3)4)15-12-7(13)5-6-8(12)14;1-7(2,3,4,5)6/h5-6H2,1-4H3;/q+1;-1

InChI key

STWZCCVNXFLDDD-UHFFFAOYSA-N

相关类别

一般描述

N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate can be used to prepare N-succinimidyl 4-[18F]fluorobenzoate ([18F]-SFB), a prosthetic group for the fluorination of biomolecules for PET imaging.

应用

Reactant for:
Synthesis of liposomal contrast agents for magnetic resonance imaging
Synthesis of thiol-reactive Cy5 derivatives
Synthesis of protein labeling molecules

其他说明

偶联剂,用于合成肽以及形成其他酰胺。即使在水溶液中,产率依然很高

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

18F-nanobody for PET imaging of HER2 overexpressing tumors
Xavier C, et al.
Nuclear Medicine and Biology, 43, 247-252 (2016)
Synthesis of 18F-labeled membrane-penetrating peptide as PET tracer
Tang G and Wang X
Journal of Nuclear Medicine, 49, 97P-97P (2008)
Synthesis and in vivo evaluation of p-18F-Fluorohippurate as a new radiopharmaceutical for assessment of renal function by PET
Awasthi V, et al.
Journal of Nuclear Medicine, 52, 147-153 (2011)
Suk Hyun Jung et al.
Nanoscale research letters, 7(1), 462-462 (2012-08-21)
Ultrasound-sensitive (sonosensitive) liposomes for tumor targeting have been studied in order to increase the antitumor efficacy of drugs and decrease the associated severe side effects. Liposomal contrast agents having Gd(III) are known as a nano-contrast agent system for the efficient
Virginia Wycisk et al.
ChemistryOpen, 6(3), 437-446 (2017-06-24)
Herein, we present a new synthetic route to cyanine-based heterobifunctional dyes and their application as fluorescent linkers between polymers and biomolecules. The synthesized compounds, designed in the visible spectral range, are equipped with two different reactive groups for highly selective

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