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Merck
CN

08339

Sigma-Aldrich

5-氨基乙酰丙酸盐 盐酸盐

≥97.0% (AT)

别名:

δ-氨基乙酰丙酸盐 盐酸盐, 5-氨基-4-氧代戊酸 盐酸盐, 5-氨基乙酰丙酸盐 盐酸盐, ALA

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About This Item

线性分子式:
NH2CH2C(O)CH2CH2COOH · HCl
CAS号:
分子量:
167.59
Beilstein:
3690651
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

质量水平

方案

≥97.0% (AT)

表单

powder or crystals

杂质

≤2% water

颜色

white to faint yellow

mp

~150 °C (dec.)

应用

peptide synthesis

储存温度

2-8°C

SMILES字符串

Cl[H].NCC(=O)CCC(O)=O

InChI

1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H

InChI key

ZLHFONARZHCSET-UHFFFAOYSA-N

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应用

5-氨基乙酰丙酸盐酸盐被用作培养大肠杆菌细胞的补充剂,用于血红素的生物合成。

生化/生理作用

5-氨基乙酰丙酸(5-ALA)可能与谷氨酸、γ-氯基丁酸(GABA)、二肽、三肽等多种转运体以及血脑屏障中的有机转运体相互作用。它还可作为叶绿素和血红素中卟啉合成的前体。5-ALA表现出植物生长调控活性。
血红素生物合成中间体。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

农药列管产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

5-Aminolevulinic acid and the blood-brain barrier-A review
Novotny A, et al.
Medical Laser Application, 18(1), 36-40 (2003)
Zhimin Yang et al.
PloS one, 9(12), e116283-e116283 (2015-01-01)
The objectives of this study were to determine whether foliar application of a chlorophyll precursor, 5-aminolevulinic acid (ALA), could mitigate salinity stress damages in perennial grass species by regulating photosynthetic activities, ion content, antioxidant metabolism, or metabolite accumulation. A salinity-sensitive
Hidetoshi Takahashi et al.
The Journal of dermatology, 41(8), 729-731 (2014-08-08)
Photodynamic therapy (PDT) is useful for superficial skin tumors such as actinic keratosis and Bowen disease. Although PDT is non-surgical and easily-performed treatment modality, irradiation apparatus is large and expensive. Using 7, 12-dimethylbenz[a]anthracene (DMBA) and 12-ο-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin papilloma
N Neittaanmäki-Perttu et al.
The British journal of dermatology, 171(5), 1172-1180 (2014-08-12)
Daylight-mediated photodynamic therapy (DL-PDT) using methyl-5-aminolaevulinate (MAL) is effective for thin, grade I, actinic keratoses (AK). There are no published studies of other photosensitizers used in DL-PDT. To compare the efficacy and adverse effects of 5-aminolaevulinic acid nanoemulsion (BF-200 ALA)
Giovanni Pagano et al.
International journal of molecular sciences, 15(11), 20169-20208 (2014-11-08)
An extensive number of pathologies are associated with mitochondrial dysfunction (MDF) and oxidative stress (OS). Thus, mitochondrial cofactors termed "mitochondrial nutrients" (MN), such as α-lipoic acid (ALA), Coenzyme Q10 (CoQ10), and l-carnitine (CARN) (or its derivatives) have been tested in

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