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应用
甲氧基聚乙二醇胺可以:
- 形成树枝状胶束,增强疏水性化合物的溶解性。
- 与抗癌药物甲氨蝶呤(MTX)共轭形成 MTX-PEG,一种潜在的药物载体。
- 与聚乙烯亚胺(PEI)形成接枝共聚物,一种潜在的非病毒基因载体。
其他说明
用于制备聚乙二醇化共轭物的低聚物,该共轭物具有降低免疫原性和延长血清半衰期的优势
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Effect of polyethylene glycol on gene delivery of polyethylenimine.
Biological & Pharmaceutical Bulletin, 26(4), 492-500 (2003)
Bioconjugate chemistry, 3(4), 295-301 (1992-07-01)
Adriamycin, a hydrophobic anticancer drug, was conjugated with poly(ethylene oxide)-poly(aspartic acid) block copolymers composed of various lengths of each block copolymer segment ranging from 1000 to 12,000 in molecular weight and from 10 to 80 units, respectively. Conjugation was achieved
Polyethylene Glycol Conjugates of Methotrexate Varying in Their Molecular Weight from MW 750 to MW 40000: Synthesis, Characterization, and Structure- Activity Relationships in Vitro and in Vivo.
Bioconjugate Chemistry, 13(4), 773-785 (2002)
Polyethylene glycol-polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in water.
Journal of Colloid and Interface Science, 273(1), 148-154 (2004)
Synthetic Communications, 22, 2417-2417 (1992)
商品
Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.
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