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Merck
CN

04936

Sigma-Aldrich

O-(6-氯-1-苯并三氮唑-1-基)-N,N,N′,N′-四甲基脲六氟磷酸酯

≥98.0% (HPLC)

别名:

1-[双(二甲氨基)亚甲基]-5-氯苯并三唑鎓 3-氧化物六氟磷酸酯, N,N,N′,N′-四甲基-O-(6-氯-1H-苯并三氮唑-1-基)脲六氟磷酸酯, HCTU

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About This Item

经验公式(希尔记法):
C11H15ClF6N5OP
分子量:
413.69
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

≥98.0% (HPLC)

表单

powder

反应适用性

reaction type: Coupling Reactions

杂质

≤0.5% water

mp

185-190 °C

应用

peptide synthesis

官能团

amine
chloro

SMILES字符串

ClC1=CC=C(N([C+](N(C)C)N(C)C)N=[N+]2[O-])C2=C1.F[P-](F)(F)(F)(F)F

InChI

1S/C11H15ClN5O.F6P/c1-15(2)11(16(3)4)18-17-10-7-8(12)5-6-9(10)13-14-17;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1

InChI key

ZHHGTMQHUWDEJF-UHFFFAOYSA-N

相关类别

应用

Reagent for:
Synthesis of near-infrared pH activatable fluorescent probes
Synthesis of human β-amyloid by Fmoc chemistry
Stereoselective Horner-Wadsworth-Emmons olefination
Covalent ligation of fluorescent peptides to quantum dots
Alkylation of human telomere sequence

其他说明

固相载体上寡核苷酸串合成,用于生成多重寡核苷酸

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1A

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Fast conventional synthesis of human beta-amyloid (1-42) on the Symphony and Prelude.
German Fuentes et al.
Advances in experimental medicine and biology, 611, 173-174 (2009-04-30)
Amit Kumar Tripathi et al.
Scientific reports, 7(1), 3384-3384 (2017-06-15)
Marine fish antimicrobial peptide, chrysophsin-1 possesses versatile biological activities but its non-selective nature restricts its therapeutic possibilities. Often small alterations in structural motifs result in significant changes in the properties of concerned proteins/peptides. We have identified GXXXXG motif in chrysophsin-1.
Hyeran Lee et al.
Bioconjugate chemistry, 22(4), 777-784 (2011-03-11)
Highly tumor selective near-infrared (NIR) pH-activatable probe was developed by conjugating pH-sensitive cyanine dye to a cyclic arginine-glycine-aspartic acid (cRGD) peptide targeting α(v)β(3) integrin (ABIR), a protein that is highly overexpressed in endothelial cells during tumor angiogenesis. The NIR pH-sensitive
Wouter A van der Linden et al.
Organic & biomolecular chemistry, 8(8), 1885-1893 (2010-05-08)
The synthesis and biological evaluation of ten Michael acceptors containing potential proteasome inhibitors are described. Cellular targets of azide containing inhibitors and were assessed in HEK293T and RAW264.7 cells by a two step labeling strategy, followed by biotin-pulldown, affinity purification
Juan B Blanco-Canosa et al.
Journal of the American Chemical Society, 132(29), 10027-10033 (2010-07-06)
Water solubilized nanoparticles such as CdSe-ZnS core-shell nanocrystals (quantum dots, QDs) have great potential in bioimaging and sensing applications due to their excellent photophysical properties. However, the efficient modification of QDs with complex biomolecules represents a significant challenge. Here, we

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