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Merck
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主要文件

安全信息

04599

Supelco

地高辛

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

别名:

异羟基洋地黄毒苷

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100 μL
CN¥5,074.24

CN¥5,074.24


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100 μL
CN¥5,074.24

About This Item

经验公式(希尔记法):
C41H64O14
CAS号:
分子量:
780.94
Beilstein:
77011
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

CN¥5,074.24


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等级

certified reference material
TraceCERT®

质量水平

产品线

TraceCERT®

表单

powder

制造商/商品名称

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

技术

gas chromatography (GC): suitable

应用

food and beverages

包装形式

neat

SMILES字符串

C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]2[C@@H](O)C[C@@H](O[C@@H]2C)O[C@H]3[C@@H](O)C[C@@H](O[C@@H]3C)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4

InChI

1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1

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一般描述

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com

生化/生理作用

一种强心苷,P-糖蛋白 (Pgp) 的底物。
一种强心苷,P-糖蛋白的底物,上调 Pgp 表达和下调 SXR(固醇类异生物受体)。

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

法律信息

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险声明

危险分类

Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

法规信息

危险化学品
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    Ali Ahmed et al.
    The American journal of medicine, 127(1), 61-70 (2013-11-22)
    Heart failure is the leading cause for hospital readmission, the reduction of which is a priority under the Affordable Care Act. Digoxin reduces 30-day all-cause hospital admission in chronic systolic heart failure. Whether digoxin is effective in reducing readmission after
    Georg Petschenka et al.
    Proceedings. Biological sciences, 280(1759), 20123089-20123089 (2013-03-22)
    Because cardenolides specifically inhibit the Na(+)K(+)-ATPase, insects feeding on cardenolide-containing plants need to circumvent this toxic effect. Some insects such as the monarch butterfly rely on target site insensitivity, yet other cardenolide-adapted lepidopterans such as the oleander hawk-moth, Daphnis nerii
    Robert C Bourge et al.
    The American journal of medicine, 126(8), 701-708 (2013-03-16)
    Heart failure is a leading cause of hospital admission and readmission in older adults. The new United States healthcare reform law has created provisions for financial penalties for hospitals with higher than expected 30-day all-cause readmission rates for hospitalized Medicare
    Chang Gong et al.
    Cancer research, 74(16), 4341-4352 (2014-07-02)
    Phyllodes tumors of breast, even histologically diagnosed as benign, can recur locally and have metastatic potential. Histologic markers only have limited value in predicting the clinical behavior of phyllodes tumors. It remains unknown what drives the malignant progression of phyllodes
    Mihai Gheorghiade et al.
    European heart journal, 34(20), 1489-1497 (2013-04-18)
    Digoxin is recommended for long-term rate control in paroxysmal, persistent, and permanent atrial fibrillation (AF). While some analyses suggest an association of digoxin with a higher mortality in AF, the intrinsic nature of this association has not been examined in

    实验方案

    Immunoassay-based methods for digitoxin or digoxin exist, but are time consuming, labor intensive, and not selective due to similarities in their chemical structures.

    LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18

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