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Merck
CN

03930590

原儿茶酸

primary reference standard

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别名:
3,4-二羟基苯甲酸, 原儿茶酸
线性分子式:
(HO)2C6H3CO2H
CAS号:
分子量:
154.12
Beilstein:
1448841
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

primary reference standard

保质期

limited shelf life, expiry date on the label

制造商/商品名称

HWI

mp

197-200 °C (dec.) (lit.)

应用

food and beverages

SMILES字符串

OC(=O)c1ccc(O)c(O)c1

InChI

1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)

InChI key

YQUVCSBJEUQKSH-UHFFFAOYSA-N

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一般描述

原儿茶酸属于多酚类化合物,一般可从玫瑰茄干花中分离得到。它可以作为一种潜在的具有抗癌作用的候选药物,参与抑制人早幼粒白血病 HL-60 细胞的生长。
由HWI制药服务股份有限公司生产和认证。
通过定量NMR获得的确切含量可在证书上找到。

应用

草药药品分析中的参比标准品

生化/生理作用

几个致癌作用的动物模型中的化学防癌剂。在后启动阶段阻断细胞增殖。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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T H Tseng et al.
Biochemical pharmacology, 60(3), 307-315 (2000-06-17)
Hibiscus protocatechuic acid (PCA), a phenolic compound isolated from the dried flower of Hibiscus sabdariffa L. (Malvaceae), demonstrated antioxidant and antitumor promotion effects in our previous study. In the present study, Hibiscus PCA was found to inhibit the survival of
In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity
Liu C-L, et al.
Food And Chemical Toxicology, 40, 635-641 (2002)
R Masella et al.
Current medicinal chemistry, 19(18), 2901-2917 (2012-04-24)
Epidemiological evidence has shown that a high dietary intake of vegetables and fruit rich in polyphenols is associated with a reduction of cancer incidence and mortality from coronary heart disease. The healthy effects associated with polyphenol consumption have made the
Saravanan Palani et al.
eLife, 10 (2021-07-17)
Actin filaments are central to numerous biological processes in all domains of life. Driven by the interplay with molecular motors, actin binding and actin modulating proteins, the actin cytoskeleton exhibits a variety of geometries. This includes structures with a curved
Paola Vitaglione et al.
The Journal of nutrition, 137(9), 2043-2048 (2007-08-22)
The metabolic fate of dietary anthocyanins (ACN) has not been fully clarified in humans. In all previous studies, the proportion of total ACN absorbed and excreted in urine was <1% intake. This study aimed to elucidate the human metabolism of

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