03394
聚（乙二醇）
tested according to Ph. Eur., 6,000
别名:
Macrogol 6,000, PEG
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线性分子式:
H(OCH2CH2)nOH
化学文摘社编号:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
产品名称
聚（乙二醇）, tested according to Ph. Eur., 6,000
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
SMILES string
C(CO)O
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
agency
tested according to Ph. Eur.
form
solid
mol wt
5000-7000
greener alternative product characteristics
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
solubility
aliphatic hydrocarbons: slightly soluble
organic solvents: soluble
application(s)
pharmaceutical (small molecule)
greener alternative category
Quality Level
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Application
聚乙二醇用于将西罗莫司固体分散体纳米粒作为亲水性载体进行表征。
Biochem/physiol Actions
聚乙二醇 (PEG) 是环氧乙烷和水的缩聚物。增强提取蛋白的复性。 这使得结晶蛋白的表征成为可能。
Preparation Note
聚乙二醇可溶于许多有机溶剂，易溶于芳香烃。也微溶于脂肪烃。
General description
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
Min-Soo Kim et al.
International journal of nanomedicine, 6, 2997-3009 (2011-12-14)
The aim of this study was to improve the physicochemical properties and bioavailability of poorly water-soluble sirolimus via preparation of a solid dispersion of nanoparticles using a supercritical antisolvent (SAS) process. First, excipients for enhancing the stability and solubility of
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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