推荐产品
生物来源
yeast
质量水平
表单
suspension
比活
~350 units/mg protein (At 25 °C with glucose-6-P as the substrate.)
包装
pkg of 1 mL (5 mg/ml)
制造商/商品名称
Roche
浓度
≥0.1-1.0 % (w/w)
技术
activity assay: suitable
颜色
white to yellowish
最佳pH
9.2
溶解性
water: miscible
适用性
suitable for UV spectrophotometry and general use
NCBI登记号
UniProt登记号
应用
life science and biopharma
异质活性
6-PGDH <0.0100%
CK <0.00100%
GR <0.0100%
HK <0.0100%
PGI <0.00200%
PGluM <0.0100%
运输
wet ice
储存温度
2-8°C
基因信息
Saccharomyces cerevisiae ... ZWF1(855480)
一般描述
葡萄糖-6-磷酸脱氢酶（G6P DH）具有活性的二聚体形式，其单体和四聚体形式是无活性的。在低NADP+和NADPH水平且在正常条件下，酶以四聚体和二聚体形式存在并保持平衡，而在高NADP +和NADPH水平时，这种平衡转变为无活性的四聚体形式。
应用
作为NADPH的辅因子再循环系统的组分。
生化/生理作用
葡萄糖-6-磷酸脱氢酶（G6P-DH）参与戊糖磷酸途径。 它能够催化葡萄糖-6-磷酸（G6P）的氧化，产生葡糖酸内酯-6-磷酸，其中NADP+同时接受氢以形成NADPH，从而维持细胞中的NADPH水平。
产品规格
污染物: <0.001% CK，<0.01% GR、HK、6-PGDH和PGluM，<0.002% PGI，<0.002% PGI
在+25℃下约350 U/mg，以葡萄糖-6-磷酸为底物。
外形
悬浮于3.2 M硫酸铵溶液中，pH约为6
制备说明
活化剂：Mg2+（5至10 mM）
其他说明
仅用于生命科学研究。不可用于诊断。
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
常规特殊物品
Matthew G S Norris et al.
Biochemical and biophysical research communications, 405(3), 388-392 (2011-01-18)
Enzyme kinetic parameters for rate equations are vital in metabolic network simulation, a major part of systems biology research efforts. Measurements of Michaelis-Menten kinetic parameters Km and Kcat have been performed for enzymes glucose-6-phosphate dehydrogenase (G6P DH) under crowded conditions
Bárbara Della Noce et al.
The Journal of biological chemistry, 298(3), 101599-101599 (2022-01-23)
Carbohydrate metabolism not only functions in supplying cellular energy but also has an important role in maintaining physiological homeostasis and in preventing oxidative damage caused by reactive oxygen species. Previously, we showed that arthropod embryonic cell lines have high tolerance
Chien-I Yang et al.
iScience, 25(8), 104756-104756 (2022-08-10)
The removal of the N-terminal formyl group on nascent proteins by peptide deformylase (PDF) is the most prevalent protein modification in bacteria. PDF is a critical target of antibiotic development; however, its role in bacterial physiology remains a long-standing question.
Neal J Dawson et al.
eLife, 9 (2020-07-31)
High-altitude environments require that animals meet the metabolic O2 demands for locomotion and thermogenesis in O2-thin air, but the degree to which convergent metabolic changes have arisen across independent high-altitude lineages or the speed at which such changes arise is
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