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经验公式（希尔记法）:
C6H11Na2O9P · xH2O
化学文摘社编号:
分子量:
304.10 (anhydrous basis)
PubChem Substance ID:
UNSPSC Code:
12352302
Beilstein/REAXYS Number:
5199009
MDL number:
NACRES:
NA.54
产品名称
D-葡萄糖-6-磷酸 二钠盐 水合物, mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g
SMILES string
O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O
InChI
1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1
InChI key
UUWJZXLTPORJKW-WYFATIGWSA-L
form
solid
mol wt
(glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)
packaging
pkg of 5 g
manufacturer/tradename
Roche
shipped in
ambient
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Other Notes
仅用于生命科学研究。不可用于诊断。
Analysis Note
Contaminants: <0.2% glucose (enzymatic)
Application
Substrate for glucose-6-phosphatase.
Biochem/physiol Actions
In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.
General description
Disodium salt
Preparation Note
77% glucose-6-P (enzymatic), 13% sodium, 8% water
C6H11O9PNa2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
涉药品监管产品
此项目有
THE ROLE OF GLUCOSE 6-PHOSPHATE IN THE REGULATION OF GLUCOSE METABOLISM IN HUMAN ERYTHROCYTES.
I A ROSE et al.
The Journal of biological chemistry, 239, 12-17 (1964-01-01)
C Villar-Palasí et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 11(7), 544-558 (1997-06-01)
Elevated blood glucose concentrations result in increased intracellular levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. In liver, blood glucose concentrations are the main factor in control of the synthesis of glycogen; insulin has only a potentiating
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